Safety of Steroid Nasal Sprays for Allergic Rhinitis: A Comparison - Pharmacology

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Steroid nasal spray


I have allergic rhinitis, and my doctor recommended nasal spray treatment.
I have two types of corticosteroid sprays: Aiminshi and Bikonar.
I've heard that corticosteroids can cause glaucoma, so I'm hesitant to use them.
Can you tell me if either of these will cause this side effect? Which one is safer to use?

Chen Xiaodi, 30~39 year old female. Ask Date: 2020/04/28

Dr. Liao Huiling reply Pharmacology


1.
The use of any medication may have side effects, and it is important to consider the treatment needs and the risks versus benefits of the disease.
2.
Steroids have a wide range of medical uses and have been clinically used for a long time, with extensive experience in their application.
Therefore, the reported side effects are also more numerous, but this does not mean that these medications are unsafe.
As long as they are used according to medical advice and with regular follow-up appointments, it is believed that the benefits for disease management will outweigh the risks.
3.
The occurrence of side effects is related to individual constitution and responses to the medication.
For information on the incidence or comparison of various side effects, it is recommended to refer to the medication's package insert.

Reply Date: 2020/04/28

More Info


When it comes to the treatment of allergic rhinitis, steroid nasal sprays, such as Aymun (艾敏釋) and Nasacort (鼻康納), are often recommended due to their effectiveness in reducing inflammation and alleviating symptoms. However, concerns about potential side effects, including the risk of glaucoma, are valid and should be addressed.

Steroid nasal sprays are classified as intranasal corticosteroids, which work by reducing inflammation in the nasal passages. They are considered first-line treatments for allergic rhinitis because they can effectively manage symptoms such as nasal congestion, runny nose, and sneezing. The use of these sprays is generally safe when used as directed, and they are preferred over systemic corticosteroids due to their localized action and lower risk of systemic side effects.

Regarding your concern about glaucoma, it is important to note that the risk of developing glaucoma from nasal steroid sprays is significantly lower compared to systemic corticosteroids. Glaucoma is primarily associated with long-term use of oral or injectable corticosteroids, which can increase intraocular pressure. The localized application of nasal sprays minimizes systemic absorption, thereby reducing the likelihood of such side effects. However, there have been rare reports of increased intraocular pressure with the use of intranasal corticosteroids, particularly in patients with pre-existing eye conditions. Therefore, it is crucial to use these medications under the guidance of a healthcare professional, especially if you have a history of eye problems.

In terms of safety between Aymun and Nasacort, both medications are effective and have similar safety profiles. The choice between them may depend on individual response and tolerance. Some patients may find one spray more effective or tolerable than the other. It is advisable to consult with your healthcare provider to determine which option may be best for you based on your specific symptoms and medical history.

In addition to the risk of glaucoma, other potential side effects of steroid nasal sprays can include nasal irritation, dryness, and occasional nosebleeds. These side effects are generally mild and can often be managed by adjusting the dosage or technique of administration. It is also important to follow the recommended dosage and frequency of use to minimize any risks.

For individuals with allergic rhinitis, it is essential to combine medication with environmental control measures. Identifying and avoiding allergens, such as pollen, dust mites, and pet dander, can significantly improve symptoms. Additionally, using saline nasal sprays can help keep the nasal passages moist and reduce irritation.

In conclusion, steroid nasal sprays like Aymun and Nasacort are effective treatments for allergic rhinitis with a relatively low risk of serious side effects, including glaucoma. It is crucial to use these medications as directed and to have regular follow-ups with your healthcare provider, especially if you have any pre-existing conditions that may increase your risk of complications. Always discuss any concerns you have about side effects with your doctor, who can provide personalized advice and alternative treatment options if necessary.

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