Your Blood Test: High Neutrophils and Low Lymphocytes Explained - Family Medicine

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White blood cell (WBC) blood test report


Hello Doctor, I recently received my blood test report.
The total white blood cell count is normal, but the neutrophils are elevated at 87.7 (normal range is 40-75), and the lymphocytes are low at 7.1 (normal range is 20-45).
The other values are monocytes (4.9), basophils (0.3), and eosinophils (0.0), which are all within normal ranges.
I would like to ask if the elevated neutrophils could be due to recent gastroenteritis causing the low lymphocyte count.
Are there any specific concerns I should be aware of? Thank you for your response, Doctor.

Ann, 20~29 year old female. Ask Date: 2020/04/30

Dr. Liao Yaopan reply Family Medicine


Hello, you may be experiencing an acute inflammatory condition that is causing changes in the proportions of various white blood cells.
It is recommended that you return to the outpatient clinic for further follow-up.
Online consultations are not equivalent to in-person medical visits and cannot provide a diagnosis or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2020/04/30

More Info


When interpreting blood test results, particularly concerning white blood cell (WBC) counts, it is essential to understand the roles of different types of white blood cells and how their levels can indicate various health conditions. In your case, you have reported a high neutrophil count of 87.7% (normal range: 40-75%) and a low lymphocyte count of 7.1% (normal range: 20-45%). The other white blood cell types, including monocytes, basophils, and eosinophils, are within normal ranges.

Neutrophils are a type of white blood cell that plays a crucial role in the body's defense against infections, particularly bacterial infections. An elevated neutrophil count, known as neutrophilia, can occur due to several reasons, including acute infections, inflammation, stress, and certain medications. In your case, the recent history of gastroenteritis (inflammation of the stomach and intestines) could indeed be a contributing factor to the increased neutrophil count. The body often responds to infections by mobilizing neutrophils to the site of infection, leading to a temporary increase in their levels in the bloodstream.

On the other hand, lymphocytes are another type of white blood cell that is primarily involved in the immune response, particularly in fighting viral infections and in the regulation of the immune system. A low lymphocyte count, known as lymphopenia, can occur due to various reasons, including acute stress, infections, certain medications, and underlying health conditions. In your case, the low lymphocyte count may be a result of the acute inflammatory response to your recent gastrointestinal infection, as the body reallocates resources to combat the immediate threat.

It is also worth noting that the total white blood cell count remains within the normal range, which suggests that while there are shifts in the types of white blood cells, the overall immune response is still functioning adequately. However, the significant deviation in the neutrophil and lymphocyte percentages indicates that your body is currently reacting to some form of stress or infection.

In terms of monitoring your health, it is essential to keep an eye on any symptoms you may experience. If you notice persistent fever, unusual fatigue, or any other concerning symptoms, it would be prudent to follow up with your healthcare provider. They may recommend further testing or monitoring to ensure that your immune system is responding appropriately and that there are no underlying issues that need to be addressed.

In summary, the high neutrophil count and low lymphocyte count in your blood test results are likely related to your recent gastrointestinal infection. While these changes can be concerning, they are often temporary and resolve as the body recovers from the infection. It is crucial to maintain communication with your healthcare provider and report any new or worsening symptoms. Regular follow-up blood tests may also be beneficial to monitor your white blood cell counts and overall health.

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