Rhabdomyolysis: When Urine Color Signals Concern - Internal Medicine

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Rhabdomyolysis and Urine Color Issues


Hello Dr.
Wu,
I have previously read your article on rhabdomyolysis that you posted on September 1, 2014.
Today, I visited an orthopedic department at a hospital (the front desk recommended me to go there) because I experienced severe thigh pain after doing squats two days ago.
I am not used to exercising, and I overdid it that day, which has resulted in pain so intense that I cannot bend my knees.
Additionally, my urine has turned a coffee color.
After explaining my situation to the doctor at the hospital, I was sent for blood tests.
The doctor informed me that the results were normal and advised me to drink plenty of water.
They also prescribed muscle relaxants and anti-inflammatory medication.

I would like to ask: my urine color clearly indicates symptoms of rhabdomyolysis, yet my blood test results are normal.
After reviewing the complications associated with rhabdomyolysis, I am very concerned that I might have this condition.
Given that I have undergone blood tests and the doctor confirmed that the results are normal, should I still be worried about having rhabdomyolysis?
P.S.
Prior to doing squats, I had no issues with my urine color.
The only related condition I can think of that would affect urine color is rhabdomyolysis.

A-Han, 20~29 year old female. Ask Date: 2020/05/06

Dr. Wu Jiyu reply Internal Medicine


One of the diagnostic tests for rhabdomyolysis is the measurement of serum creatine phosphokinase (CPK) levels.
If the test results are normal and the pain subsequently decreases, with normal urine color, there is no need for concern.
It is important to maintain a regular exercise routine, ensuring it is moderate and not excessive.
Remember that proper warm-up exercises are key to a healthy lifestyle.
Thank you for your inquiry; the Nephrology Department at Changhua Hospital cares about your well-being.

Reply Date: 2020/05/06

More Info


Rhabdomyolysis is a serious condition that occurs when muscle tissue breaks down and releases its contents into the bloodstream, which can lead to kidney damage. One of the hallmark signs of rhabdomyolysis is dark, tea-colored urine, which is often due to the presence of myoglobin, a protein released from damaged muscles. Given your recent experience with deep squats and the subsequent muscle pain and dark urine, it’s understandable that you are concerned about the possibility of rhabdomyolysis.

From your description, it seems that you experienced significant muscle soreness after an intense workout, which is not uncommon, especially if you are not accustomed to such physical activity. The coffee-colored urine you mentioned is indeed a symptom that can be associated with rhabdomyolysis. However, it is important to note that the diagnosis of rhabdomyolysis is typically confirmed through blood tests that measure levels of creatine kinase (CK), myoglobin, and other markers of muscle damage.
In your case, you mentioned that the blood tests returned normal results. This is a crucial point. Normal blood test results, especially for CK levels, would suggest that there is no significant muscle breakdown occurring at this time. While it is possible to have mild muscle injury without a dramatic rise in CK levels, the absence of elevated levels in your blood tests is reassuring.
It’s also worth noting that muscle soreness and dark urine can occur for various reasons, including dehydration, certain medications, or even dietary factors. Since your doctor advised you to stay hydrated and prescribed muscle relaxants and anti-inflammatory medication, it seems they are taking a cautious approach to manage your symptoms. Drinking plenty of fluids is essential, as it helps to flush out any myoglobin that may be present in your urine and supports kidney function.

If you continue to experience dark urine or if your symptoms worsen, it would be wise to follow up with your healthcare provider. They may consider repeating blood tests or conducting additional tests to monitor your kidney function, especially if you notice any signs of kidney distress, such as decreased urine output, swelling, or persistent fatigue.

In summary, while your symptoms initially raised concerns about rhabdomyolysis, the normal blood test results are a positive indicator that you may not have this condition. However, it is essential to remain vigilant and maintain communication with your healthcare provider. If you have any further concerns or if your symptoms change, do not hesitate to seek medical advice. Your health and well-being are the top priority, and staying informed about your condition will help you manage it effectively.

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