Managing Bronchiectasis: Long-Term Antibiotic Use and Side Effects - Pulmonology

Share to:

Bronchiectasis


I have bronchiectasis and have been coughing up blood along with phlegm.
The doctor prescribed erythromycin for a year, and I'm unsure if I really need to take it for that long.
For the past six months, I've been experiencing recurrent hemoptysis, and later the doctor prescribed a week of antibiotics (Pefloxacin) and a corticosteroid (Budesonide), which seem to have controlled the coughing up of blood.
I'm wondering if it was the antibiotics that helped control it.
Previously, I was on erythromycin and a mucolytic agent for three months.
Should I continue taking erythromycin for the full year? I'm concerned about potential side effects from such a long duration of treatment.

Mi Mi, 50~59 year old female. Ask Date: 2020/05/06

Dr. Yang Wenda reply Pulmonology


Hello: It is recommended to take it for one year based on a European research report.
In the study, the treatment group that received treatment for one year showed a reduction in the frequency of episodes.
However, there are no research reports on treatment durations of 3 months or 6 months, so it is unclear whether taking it for only 3 months or 6 months has any definitive effects.
If any side effects or heart diseases occur, then consider discontinuing erythromycin!

Reply Date: 2020/05/06

More Info


Managing bronchiectasis, especially when it involves symptoms like hemoptysis (coughing up blood) and sputum production, can be quite challenging. Your doctor’s recommendation for long-term antibiotic therapy, such as erythromycin, is not uncommon in managing chronic respiratory conditions like bronchiectasis. This approach is primarily aimed at controlling bacterial infections and reducing inflammation in the airways, which can help alleviate symptoms and prevent exacerbations.


Long-Term Use of Antibiotics
1. Duration of Treatment: The recommendation to take erythromycin for a year is based on the understanding that chronic infections can be a significant contributor to the symptoms of bronchiectasis. Long-term antibiotic therapy can help reduce the frequency of exacerbations and improve overall lung function. However, the exact duration can vary based on individual response and the severity of the condition. It’s essential to have regular follow-ups with your healthcare provider to assess the effectiveness of the treatment and make adjustments as necessary.

2. Efficacy of Short-Term Antibiotics: You mentioned that after taking a week of another antibiotic (likely a different class), you noticed an improvement in your symptoms. This could indicate that your condition may have been exacerbated by an acute bacterial infection that responded well to the short-term antibiotic. It’s also possible that the combination of treatments (erythromycin and the new antibiotic) is working synergistically to control your symptoms.


Concerns About Side Effects
3. Potential Side Effects: Long-term use of antibiotics, including erythromycin, can lead to several side effects. Common side effects include gastrointestinal disturbances (nausea, diarrhea), potential liver toxicity, and the risk of developing antibiotic resistance. Additionally, prolonged use can disrupt the normal flora of the gut, leading to conditions like Clostridium difficile infection, which can be serious.

4. Monitoring and Management: It’s crucial to have regular check-ups with your healthcare provider to monitor for side effects and assess the need for continued antibiotic therapy. Your doctor may recommend periodic liver function tests and other evaluations to ensure that the treatment is not causing harm.


Alternative Strategies
5. Adjunct Therapies: In addition to antibiotics, other treatments may be beneficial in managing bronchiectasis. These can include bronchodilators, inhaled corticosteroids, and pulmonary rehabilitation. The use of mucolytics can help in thinning mucus, making it easier to clear from the airways. Discussing these options with your healthcare provider can provide a more comprehensive management plan.

6. Lifestyle Modifications: Staying hydrated, practicing good respiratory hygiene, and engaging in regular physical activity can also help manage symptoms. Avoiding smoking and exposure to pollutants is crucial in maintaining lung health.


Conclusion
In summary, while long-term antibiotic therapy like erythromycin can be an effective strategy for managing bronchiectasis, it’s essential to weigh the benefits against potential side effects. Regular follow-ups with your healthcare provider are vital to monitor your condition and adjust treatment as necessary. If you have concerns about the duration of your antibiotic therapy or experience any adverse effects, do not hesitate to discuss these with your doctor. They can provide personalized advice based on your specific health needs and circumstances.

Similar Q&A

Long-Term Antibiotic Use in Children: Risks and Effectiveness Explained

Hello, my 13-year-old daughter has a history of asthma and lung collapse. Recently, she had a severe cold that led to coughing up blood. The doctor diagnosed her with bronchiectasis and noted low blood oxygen levels (92-95). The treating physician has been prescribing antibiotics...


Dr. Pei Rensheng reply Pediatrics
Dear Jack, Hello! 1. The treatment for bronchiectasis in children includes chest physiotherapy and antibiotic therapy. 2. Potential underlying causes need to be ruled out, including immunodeficiency, foreign body aspiration, and other conditions such as congenital structural ...

[Read More] Long-Term Antibiotic Use in Children: Risks and Effectiveness Explained


Can Bronchiectasis Be Cured with Medical Treatment? Insights and Options

Hello Dr. Tsai: I am currently suffering from bronchiectasis and have been under treatment by my physician for six months, but the symptoms still persist. I would like to ask Dr. Tsai if it is possible to fully recover from bronchiectasis with medical treatment, or if there are o...


Dr. Jian Linzhen reply Pulmonology
Bronchiectasis refers to the abnormal and permanent dilation of the bronchi. In patients with this condition, the airways become distorted and lax, often obstructed by thick, and sometimes purulent, secretions, leading to prominent clinical symptoms such as productive cough and d...

[Read More] Can Bronchiectasis Be Cured with Medical Treatment? Insights and Options


Is There a Link Between Bronchiectasis and Long-Term Smoking?

Is bronchiectasis related to long-term smoking? I learned from medical news that the new drug "Oxis Turbuhaler" is now covered by health insurance in Taiwan. Can I request my doctor to prescribe this medication during my visit? Thank you for your time in answering.


Dr. Zhang Zhengda reply Pulmonology
1. Bronchiectasis is caused by inflammation and subsequent damage to the bronchi in the lungs, and it can also be congenital. It is not directly related to smoking. However, patients with bronchiectasis should refrain from smoking to prevent further deterioration of bronchial fun...

[Read More] Is There a Link Between Bronchiectasis and Long-Term Smoking?


Understanding Bronchiectasis: Key Questions and Answers for Patients

1. For patients with bronchiectasis, the daily sputum production can range from approximately 30 cc to 100 cc, but this can vary widely depending on the severity of the condition. 2. Yellow sputum may indicate a bacterial infection, suggesting that the lung condition could still...


Dr. Li Shiwei reply Pulmonology
Reply: Hello, 1. The amount of sputum in patients with bronchiectasis varies from person to person and is related to the extent and location of the bronchiectasis, as well as the presence of infection. 2. An increase in sputum volume or a change to a yellow color often indica...

[Read More] Understanding Bronchiectasis: Key Questions and Answers for Patients


Related FAQ

Bronchiectasis

(Pulmonology)

Bronchitis

(Pulmonology)

Medication Side Effects

(Pulmonology)

Medication Consultation

(Pulmonology)

Chronic Cough

(Pulmonology)

Aspiration Pneumonia

(Pulmonology)

Bronchial Fibrosis

(Internal Medicine)

Mycobacterium Tuberculosis

(Pulmonology)

Throat Itching

(Pulmonology)

Smoking Cessation

(Pulmonology)