Alcohol Disinfection: Risks and Recommendations - Pharmacology

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Questions related to disinfectant alcohol?


Hello, doctor.
Due to the recent pneumonia issues, I would like to ask you some questions.
According to the CDC website, hand hygiene should involve using alcohol with at least 60% concentration.
However, I have also seen reports from various domestic and international websites stating that excessive use of alcohol can lead to symptoms of "dishpan hands" and a decrease in hand immunity.

1.
What constitutes excessive use? Is it using it every ten minutes, or is it even more frequent than that?
2.
Regarding the decrease in immunity, is there any truth to this, or is it a baseless concern? Thank you for taking the time to answer my questions.

Jie, 20~29 year old female. Ask Date: 2020/05/18

Dr. Zheng Shuwen reply Pharmacology


Hello: Although alcohol has certain disinfecting and antibacterial properties, it is only a temporary cleaning solution when handwashing is not possible and cannot completely replace the act of washing hands.
Therefore, frequent use is not recommended.
It is suggested that you carry travel-sized neutral soap with you and implement the "inner and outer grip with strong wrist" technique while washing hands, as this is the most effective method for disease prevention.
Alcohol-based hand sanitizers do not decrease the immune strength of the hands; rather, consuming alcohol is the primary cause of reduced immunity.
If you experience discomfort in your hands after using cleaning products, such as rashes, dryness, or burning sensations, please consult a dermatologist promptly.
If you have any other questions, feel free to call during office hours.
Thank you.
Consultation phone: 03-3698553.
Office hours: Monday to Tuesday: 08:30 - 21:30; Wednesday to Friday: 08:30 - 17:30; Saturday: 08:30 - 13:30.
Thank you.
Taoyuan Sanatorium cares about you.

Reply Date: 2020/05/18

More Info


When it comes to the use of alcohol for disinfection, particularly in the context of the recent pandemic, there are several important considerations regarding its effectiveness, risks, and recommendations for safe use. The Centers for Disease Control and Prevention (CDC) recommends using hand sanitizers that contain at least 60% alcohol to effectively kill germs and viruses, including the coronavirus responsible for COVID-19. However, concerns have arisen regarding the potential negative effects of excessive alcohol use on skin health and immune function.

1. Understanding Excessive Use: The term "excessive use" can vary depending on context. Generally, using hand sanitizer or alcohol-based disinfectants every ten minutes could be considered excessive, especially if it leads to skin irritation or damage. The CDC suggests using hand sanitizer when soap and water are not available, and it is important to apply it correctly—covering all surfaces of the hands and rubbing them together until they feel dry. Frequent use, particularly in the absence of moisturizing agents, can lead to skin conditions such as dermatitis, which may manifest as dryness, cracking, or irritation.
2. Impact on Immune Function: The concern about decreased immune function due to frequent use of alcohol-based sanitizers is a topic of ongoing research. While there is no substantial evidence to suggest that using alcohol-based hand sanitizers in moderation directly weakens the immune system, excessive use can compromise the skin barrier. The skin is a critical component of the immune system, serving as the first line of defense against pathogens. When the skin becomes damaged or irritated, it may be less effective at preventing infections.
Moreover, the concept of "rich hands" or "dishpan hands" refers to the condition where the skin becomes overly dry and cracked due to frequent washing or use of alcohol-based products. This condition can indeed lead to an increased risk of infections, as cracks in the skin can serve as entry points for pathogens.
To mitigate these risks, it is advisable to follow these recommendations:
- Use Alcohol Wisely: Use alcohol-based hand sanitizers when necessary, especially in situations where soap and water are not available. However, if you are in a situation where you can wash your hands with soap and water, that is generally the preferred method.

- Moisturize: After using alcohol-based sanitizers, apply a good quality moisturizer to help maintain skin hydration and integrity. Look for products that contain ingredients like glycerin, aloe vera, or hyaluronic acid, which can help replenish moisture.

- Monitor Skin Health: Pay attention to how your skin reacts to frequent use of alcohol-based products. If you notice signs of irritation, redness, or cracking, consider reducing the frequency of use and consult a dermatologist if necessary.

- Educate on Proper Techniques: Ensure that hand hygiene practices are well understood. For instance, hand sanitizers should be used in sufficient amounts (typically a dime-sized amount) and should be rubbed into the hands for at least 20 seconds until dry.

In summary, while alcohol-based disinfectants are effective in reducing the spread of infectious diseases, it is crucial to use them judiciously to avoid adverse effects on skin health and potential impacts on immune function. Balancing effective hand hygiene with skin care will help maintain both cleanliness and skin integrity.

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