Are Gallstone Medications Linked to Skin Allergies and Redness? - Gastroenterology and Hepatology

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Is there a connection between medication for gallstones and skin allergies causing redness and swelling?


Hello, I was diagnosed with acute cholecystitis due to gallstones in February 2019, which led to acute pancreatitis.
I was hospitalized and received intravenous antibiotics, and after the inflammation subsided, I was discharged without having my gallbladder removed, as I went abroad to study.
I am currently studying in the UK and have recently experienced abdominal cramping, jaundice, and I have been taking the medication Kantec (hymecromone) that was prescribed by my doctor at that time.
After taking it, I started to develop numerous pimples and redness on my face.
Could you please advise if this is a side effect of the medication or if it is related to my gallstones? Thank you.

Xu Xiaoqi, 30~39 year old female. Ask Date: 2020/06/09

Dr. Chen Shidian reply Gastroenterology and Hepatology


I'm sorry, I don't have experience with that medication.
Gallstones do not affect the skin.

Reply Date: 2020/06/09

More Info


Gallstones can lead to a variety of complications, including acute cholecystitis and pancreatitis, as you have experienced. The medications prescribed for gallstone-related issues, such as Kantec (hymecromone), are generally used to alleviate symptoms associated with gallstones, such as abdominal pain and discomfort. However, it is important to note that any medication can potentially cause side effects, including skin reactions.

In your case, the appearance of acne-like lesions and redness on your face after taking Kantec could indeed be a side effect of the medication. Hymecromone is not commonly associated with skin allergies, but individual reactions can vary. It is also possible that the changes in your skin condition could be related to other factors, such as dietary changes, stress, or environmental factors, especially since you are studying abroad in a different climate.

Skin reactions can manifest in various forms, including rashes, redness, and acne-like eruptions. These reactions can be triggered by medications, but they can also arise from underlying conditions or external irritants. Given your history of gallstones and the recent abdominal discomfort, it is crucial to consider that your body may be reacting to multiple factors simultaneously.

If you suspect that the medication is causing your skin issues, it is advisable to stop taking it and consult with a healthcare professional. They can evaluate your symptoms, review your medication history, and possibly recommend alternative treatments for your gallstone-related symptoms that may not have the same side effects. Additionally, they may suggest dermatological treatments to address the skin issues you are experiencing.

In the meantime, here are some general recommendations for managing skin reactions:
1. Avoid Irritants: Stay away from harsh skincare products, fragrances, and other potential irritants that could exacerbate your skin condition.

2. Moisturize: Use a gentle, non-comedogenic moisturizer to help soothe your skin and prevent dryness.

3. Hydration: Ensure you are drinking plenty of water, as hydration can help maintain skin health.

4. Diet: Pay attention to your diet, as certain foods can trigger skin reactions. Consider keeping a food diary to identify any potential triggers.

5. Consult a Dermatologist: If the skin issues persist, it may be beneficial to see a dermatologist who can provide targeted treatments and advice.

6. Monitor Symptoms: Keep track of any changes in your skin condition and overall health, and report these to your healthcare provider.

In conclusion, while it is possible that Kantec could be contributing to your skin issues, it is essential to consider all potential factors. Consulting with a healthcare professional will provide you with the best course of action to address both your gallstone symptoms and skin concerns.

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