Are There Effective Treatments for Liver Cirrhosis in Taiwan?

Is there a specific medication for cirrhosis?

Hello, Director.
I am a bride from Mainland China.
My sister-in-law has had hepatitis B since she was young.
Due to the lack of obvious symptoms, she did not pay much attention to managing this condition.
Now at 40 years old, with four children, my sister-in-law has progressed from hepatitis B to severe cirrhosis of the liver.
Recently, her condition worsened to the point where she had to undergo surgery to remove her spleen.
My brother is very worried about her and would like to know if there are any effective treatments or medications for cirrhosis available in Taiwan.
She has been taking medications prescribed by hospitals in Mainland China, but her condition remains serious.
We sincerely hope to receive your response and would greatly appreciate any guidance you can provide.
Thank you!

Miss Yang, 40~49 year old female. Ask Date: 2020/06/09

Dr. Chen Shidian reply Gastroenterology and Hepatology

It is recommended to use antiviral medications long-term (such as Baraclude or Hepsera) and to undergo regular ultrasound monitoring.

Reply Date: 2020/06/09

More Info

Liver cirrhosis is a serious condition that arises from chronic liver damage, often due to hepatitis B, hepatitis C, alcohol abuse, or fatty liver disease. In your case, your sister-in-law's progression from chronic hepatitis B to severe liver cirrhosis is concerning, especially given her age and the fact that she has undergone a splenectomy due to complications.
Currently, there is no "cure" for liver cirrhosis, but there are effective management strategies and treatments available that can help slow the progression of the disease and manage its complications. In Taiwan, as in many parts of the world, the treatment of liver cirrhosis primarily focuses on addressing the underlying cause of liver damage and managing symptoms.

1. Antiviral Therapy: For patients with hepatitis B-related cirrhosis, antiviral medications such as tenofovir (Viread) and entecavir (Baraclude) are commonly prescribed. These medications can help suppress the hepatitis B virus, reducing liver inflammation and preventing further liver damage. It is crucial for your sister-in-law to be regularly monitored by a healthcare professional to assess her liver function and determine the most appropriate antiviral therapy.

2. Management of Complications: Cirrhosis can lead to various complications, including portal hypertension, variceal bleeding, ascites, and hepatic encephalopathy. Management strategies may include:
- Beta-blockers: These can be used to reduce portal hypertension and the risk of variceal bleeding.

- Diuretics: Medications like spironolactone can help manage fluid retention and ascites.

- Lactulose: This can be used to treat hepatic encephalopathy by reducing ammonia levels in the blood.

3. Lifestyle Modifications: It is essential for patients with liver cirrhosis to adopt a healthy lifestyle. This includes avoiding alcohol, maintaining a balanced diet, and managing weight. Regular follow-ups with a hepatologist are crucial for monitoring liver health and adjusting treatment as necessary.

4. Liver Transplantation: In cases of decompensated cirrhosis where liver function is severely impaired, a liver transplant may be the only option. This is typically considered when the patient has significant complications and a poor prognosis.

5. Regular Monitoring: Regular check-ups, including blood tests and imaging studies, are vital for assessing liver function and detecting any potential complications early. In Taiwan, healthcare providers often recommend routine screenings for liver cancer (hepatocellular carcinoma) in patients with cirrhosis, as they are at increased risk.

In summary, while there is no specific "miracle drug" for liver cirrhosis, effective treatments are available to manage the condition and improve quality of life. It is essential for your sister-in-law to work closely with her healthcare team to determine the best course of action based on her specific situation. Early intervention and consistent management can significantly impact her health outcomes. If she is currently on medications prescribed in mainland China, it may be beneficial to consult with a hepatologist in Taiwan to explore additional treatment options and ensure she receives comprehensive care.

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