Kidney Health: Can You Improve Glomerular Filtration Rate? - Family Medicine

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I would like to ask the doctor about health check-up issues?


I would like to ask the doctor because I recently had a health check-up.
Today, I reviewed the report, and overall, it looks good; my creatinine and urine protein levels are normal.
However, my glomerular filtration rate (GFR) seems a bit low at 79.24, compared to around 86 last year.
I'm not sure why it has decreased so much, and since I usually eat out a lot, I'm a bit worried.
Based on this rate of decline, will it drop to the 60s next year? I would like to ask the doctor if the GFR can be improved.
What should I pay attention to in my daily life for better kidney health?

Niming, 40~49 year old female. Ask Date: 2020/06/09

Dr. Xiao Yongxun reply Family Medicine


Dear Mr.
Anonymous:
The formula for estimating the estimated Glomerular Filtration Rate (eGFR) (units: ml/min/1.73m²) is as follows:
For males:
eGFR = 186 × (serum creatinine)⁻¹⁵⁴ × (age)⁻⁰²⁰³
For females:
eGFR = 186 × (serum creatinine)⁻¹⁵⁴ × (age)⁻⁰²⁰³ × 0.742
Due to the complexity and invasiveness of normal physiological experimental methods, they cannot be applied to many patients or the general population.
Therefore, the above regression equation for eGFR is used to roughly estimate kidney function.
As indicated by the parameters in the equation, age, sex, and serum creatinine are factors that influence the estimated eGFR.
Generally, as age and serum creatinine levels increase, the estimated eGFR decreases.

Using this value, chronic kidney disease (CKD) can be classified into five stages:
- Stage 1: eGFR > 90 ml/min/1.73m² with kidney damage (normal kidney function but with conditions such as proteinuria or hematuria).

- Stage 2: eGFR 60-90 ml/min/1.73m² (mild chronic kidney failure, but with proteinuria or hematuria).

- Stage 3: eGFR 30-60 ml/min/1.73m² (moderate chronic kidney failure).

- Stage 4: eGFR 15-30 ml/min/1.73m² (severe chronic kidney failure).

- Stage 5: eGFR < 15 ml/min/1.73m² (end-stage renal disease).

This clinical assessment clearly indicates that, in addition to eGFR, other objective evidence or symptoms of kidney damage should also be considered.
Please be sure to discuss this with your family physician or visit a nephrology outpatient clinic at a regional hospital for further consultation.

General kidney care primarily involves reducing the burden on the kidneys:
1.
Limit consumption of fried and grilled foods.

2.
Maintain a moderate intake of protein.

3.
Keep salt intake low.

4.
Control blood pressure effectively.

5.
Manage blood sugar levels.

6.
Regulate blood lipid levels.

7.
When kidney function is normal, drink plenty of warm water and avoid excessive intake of beverages.

Reply Date: 2020/06/09

More Info


Improving kidney health, particularly the glomerular filtration rate (GFR), is a significant concern for many individuals, especially those with risk factors such as diabetes, hypertension, or a family history of kidney disease. Your recent health check indicates a GFR of 79.24 mL/min, which is lower than the previous year's measurement of 86 mL/min. While this decline may seem alarming, there are several strategies you can adopt to help stabilize or potentially improve your kidney function.


Understanding GFR and Kidney Health
GFR is a critical measure of kidney function, reflecting how well your kidneys filter waste and excess fluids from your blood. A GFR below 60 mL/min for three months or more indicates chronic kidney disease (CKD). However, a GFR of 79.24 mL/min is still considered to be in the normal range, albeit on the lower end. It's essential to monitor this value regularly, especially if you have risk factors for kidney disease.


Factors Influencing GFR
Several factors can influence GFR, including:
1. Hydration: Dehydration can lead to a temporary decrease in GFR. Ensure you are drinking enough water throughout the day, especially if you consume a lot of salty or processed foods, which can lead to fluid retention and dehydration.

2. Diet: A diet high in sodium, processed foods, and animal proteins can negatively impact kidney function. Since you mentioned that you often eat out, try to choose meals that are lower in salt and protein. Incorporating more fruits, vegetables, and whole grains can be beneficial.

3. Blood Sugar Control: If you have diabetes, maintaining stable blood sugar levels is crucial. High blood sugar can damage the kidneys over time. Regular monitoring and adherence to your prescribed medication can help manage your blood sugar levels effectively.

4. Blood Pressure Management: High blood pressure can also harm kidney function. Aim for a blood pressure reading below 130/80 mmHg. Regular exercise, a balanced diet, and medication (if prescribed) can help keep your blood pressure in check.

5. Avoiding Nephrotoxic Substances: Certain medications and substances can harm the kidneys. Non-steroidal anti-inflammatory drugs (NSAIDs), certain antibiotics, and contrast dyes used in imaging studies can be harmful. Always consult your healthcare provider before taking new medications.


Lifestyle Modifications for Kidney Health
1. Dietary Adjustments: Focus on a kidney-friendly diet. This typically includes:
- Reducing sodium intake (aim for less than 2,300 mg per day).

- Limiting protein intake, especially from animal sources, as excessive protein can increase the kidneys' workload.

- Incorporating foods rich in omega-3 fatty acids (like fish), which may help reduce inflammation.

2. Regular Exercise: Engaging in regular physical activity can help maintain a healthy weight, control blood pressure, and improve overall health. Aim for at least 150 minutes of moderate aerobic activity each week.

3. Routine Monitoring: Regular check-ups with your healthcare provider to monitor kidney function, blood pressure, and blood sugar levels are essential. This allows for early detection of any changes and timely intervention.

4. Stress Management: Chronic stress can negatively impact overall health, including kidney function. Techniques such as yoga, meditation, or deep-breathing exercises can be beneficial.

5. Avoid Smoking and Limit Alcohol: Smoking and excessive alcohol consumption can worsen kidney function. If you smoke, seek help to quit, and limit alcohol intake to moderate levels.


Conclusion
While a decline in GFR can be concerning, there are numerous proactive steps you can take to support your kidney health. By focusing on a balanced diet, maintaining hydration, managing blood sugar and blood pressure, and adopting a healthy lifestyle, you can potentially stabilize or improve your GFR. Always consult with your healthcare provider before making significant changes to your diet or lifestyle, especially if you have underlying health conditions. Regular monitoring and early intervention are key to maintaining kidney health and preventing further decline.

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