Pituitary Tumors: Surgery, Recovery, and Risks Explained - Neurosurgery

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Pituitary tumor


Recently, during a medical examination at the hospital, a pituitary tumor approximately 1.7 cm in size was discovered.
Blood tests showed prolactin levels at 29 and growth hormone levels at 79, with other results being normal.
I would like to ask if, in general, complete removal of the tumor will lead to a gradual return to normal levels, or if incomplete removal will still result in abnormal hormone levels.
Is navigational surgery for pituitary tumors considered advanced in Taiwan? Are there specific concerns regarding potential pressure on the eyes, olfactory function, and any relation to the ears during the surgery? Thank you.

Shaohua, 30~39 year old female. Ask Date: 2020/06/11

Dr. Zhao Shaoqing reply Neurosurgery


In Taiwan, this technique is very advanced, allowing for the removal of tumors through the nasal cavity using an endoscope.
Navigation guidance significantly enhances the precision of the surgery.
After a successful operation, hormone levels can return to normal ranges.
A small number of patients may experience hypofunction.
Tumors larger than 2 centimeters may potentially affect neurological function.

Reply Date: 2020/06/11

More Info


Pituitary tumors, also known as pituitary adenomas, are growths that occur in the pituitary gland, a small gland located at the base of the brain that plays a crucial role in regulating hormones. These tumors can be classified as functional or non-functional, depending on whether they produce excess hormones. In your case, the elevated prolactin (29) and growth hormone (79) levels suggest that the tumor is likely a functional adenoma, which can lead to various hormonal imbalances and symptoms.

Surgical intervention is often the primary treatment for pituitary tumors, especially if they are causing significant symptoms or hormonal imbalances. The most common surgical approach is transsphenoidal surgery, where the tumor is accessed through the nasal cavity. This method is generally considered safe and effective, and in Taiwan, it is performed by experienced neurosurgeons who are well-versed in this technique.

Regarding your specific questions about recovery and risks:
1. Recovery After Surgery: After the complete removal of a pituitary tumor, many patients experience a gradual normalization of hormone levels. However, the extent of recovery can vary based on several factors, including the size of the tumor, the duration of hormonal imbalance prior to surgery, and whether the tumor was completely resected. In some cases, if any tumor remnants remain, hormone levels may not return to normal, and further treatment may be necessary.

2. Risks and Complications: One of the significant risks associated with pituitary surgery is damage to surrounding structures, particularly the optic nerves, which can affect vision. Surgeons take great care to avoid this, but it is a potential risk. Additionally, there may be concerns regarding the olfactory nerves (responsible for smell) and the cranial nerves that affect hearing and balance. Post-operative monitoring is crucial to detect any complications early.

3. Post-Surgery Monitoring: After surgery, patients typically undergo regular follow-up appointments, including blood tests to monitor hormone levels and imaging studies (like MRI) to ensure there is no tumor recurrence. It is essential to communicate any new symptoms or concerns to your healthcare provider promptly.

4. Long-term Outlook: The prognosis for patients with pituitary tumors is generally favorable, especially when the tumor is completely removed. However, some patients may require additional treatments, such as medication or radiation therapy, depending on the tumor type and whether it has recurred.

5. Lifestyle Considerations: Post-surgery, it is advisable to maintain a healthy lifestyle, including a balanced diet and regular exercise, to support recovery and overall well-being. Additionally, managing stress and ensuring adequate sleep can also aid in hormonal balance.

In conclusion, while the surgery for pituitary tumors is well-established and generally safe, it is essential to have a thorough discussion with your neurosurgeon about the specific risks and benefits in your case. They can provide personalized insights based on the tumor's characteristics and your overall health. Regular follow-up care is crucial for monitoring recovery and managing any potential complications.

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