What is Valsartan and How Does It Affect the Human Body? - Pharmacology

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Valsartan is an angiotensin II receptor blocker (ARB) used primarily to treat high blood pressure and heart failure. It works by relaxing blood vessels, which helps to lower blood pressure and improve blood flow. In terms of its effects on the body, Valsartan can help reduce the risk of stroke, heart attack, and kidney problems in patients with high blood pressure. However, it may also cause side effects such


Hello, doctor.
My grandfather has been prescribed (Jian An Xin Mo) due to coronary artery blockage, and the medication label states it contains 80 mg of Valsartan.
Could you please explain what Valsartan is and what effects it may have on the human body?

Xiao Mai Yi, 20~29 year old female. Ask Date: 2020/06/18

Dr. Huang Shenggang reply Pharmacology


Hello, Little Ant: Thank you for your question.
Valsartan can be used alone or in combination with other medications to treat hypertension.
It can also be used as a substitute for ACE inhibitors (Angiotensin-Converting Enzyme Inhibitors) in the treatment of heart failure.
Valsartan is an angiotensin receptor blocker that works by blocking certain chemicals in the blood vessels, leading to relaxation of the blood vessels and a reduction in blood pressure.
Although the side effects of this medication are not common, they can still occur.

1.
If you experience any of the following symptoms severely or if they do not go away, please notify your physician as soon as possible: dizziness, headache, excessive fatigue, diarrhea, stomach pain, back pain, joint pain.

2.
If you have any of the following symptoms, please contact your physician immediately: swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower limbs; hoarseness; difficulty breathing or swallowing; fainting.
Thank you.

Reply Date: 2020/06/18

More Info


Valsartan is a medication that belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). It is primarily used to treat high blood pressure (hypertension) and heart failure. By blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, Valsartan helps to relax and widen blood vessels, which in turn lowers blood pressure and improves blood flow. This mechanism is particularly beneficial for patients with conditions such as coronary artery disease, as it can help reduce the workload on the heart and improve overall cardiovascular health.

In your grandfather's case, Valsartan is likely prescribed due to his coronary artery blockage. Managing blood pressure is crucial in such situations, as high blood pressure can exacerbate heart problems and increase the risk of heart attacks or strokes. By lowering blood pressure, Valsartan can help protect the heart and improve the quality of life for patients with cardiovascular issues.

While Valsartan is generally well-tolerated, like all medications, it can have side effects. Common side effects include dizziness, headache, fatigue, abdominal pain, and back pain. These side effects are usually mild and may resolve as the body adjusts to the medication. However, it is essential to monitor for more severe reactions. If your grandfather experiences symptoms such as swelling of the face, throat, or tongue, difficulty breathing or swallowing, or severe dizziness, he should seek medical attention immediately, as these could be signs of an allergic reaction.

It's also important to note that Valsartan can interact with other medications, so it's crucial for your grandfather to inform his healthcare provider about all the medications he is taking, including over-the-counter drugs and supplements. Additionally, regular monitoring of kidney function and electrolyte levels is recommended, as Valsartan can affect kidney function in some patients.

In summary, Valsartan is a valuable medication for managing high blood pressure and heart failure, particularly in patients with coronary artery disease. Its ability to relax blood vessels can significantly improve cardiovascular health. However, it is essential to be aware of potential side effects and interactions with other medications. Regular follow-up with healthcare providers will help ensure that your grandfather receives the best possible care while on this medication. If there are any concerns or unusual symptoms, it is always best to consult with a healthcare professional for guidance.

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