Can Medication Help Expel a Nonviable Embryo? Ectopic Pregnancy Care - Obstetrics and Gynecology

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If the embryo is not viable, can medication be used to induce expulsion? If it is absorbed by the body, is there a need for postpartum confinement?


Hello Doctor: I have polycystic ovary syndrome and have been taking medication to regulate my menstrual cycle.
During my follow-up appointment on June 8, I found out I was pregnant, and my initial blood test showed a pregnancy hormone level of 936.
On June 12, my blood test showed over 300, and on June 13, it was over 500.
However, by June 19, the level had dropped to 168.
The doctor indicated that the embryo had failed, and during each visit, no gestational sac was observed, leading to a diagnosis of ectopic pregnancy.
During this time, I have also experienced intermittent pain and discomfort in both ovaries, lasting about 10 minutes each time.
The doctor mentioned this was normal.
I only had one instance of brown discharge, and there has been no other bleeding.
Currently, the doctor is monitoring whether the embryo will be absorbed by the body or if there is a risk of a ruptured fallopian tube.
I would like to know why I cannot directly take medication or receive an injection to expel the tissue.
I am a bit scared that if the fallopian tube ruptures, I will lose one of them.
I am also concerned about the difficulty of conceiving with polycystic ovary syndrome.
If, by chance, the embryo is absorbed by my body, will I still need to follow a miscarriage diet? I apologize for the many questions, and thank you for your help.

Elaine, 20~29 year old female. Ask Date: 2020/06/23

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the treatment methods for ectopic pregnancy and miscarriage are different.
It is recommended to follow up with your physician for scheduled visits and examinations.
Only after confirming the diagnosis can the treatment approach and subsequent adjustments be determined.
Thank you! Wishing you safety and health.
Dr.
Zhang

Reply Date: 2020/06/23

More Info


When dealing with a suspected ectopic pregnancy, especially in the context of a nonviable embryo, it is crucial to understand the medical options available and the implications of each treatment. In your case, the situation involves a history of polycystic ovary syndrome (PCOS) and fluctuating hCG levels, which can complicate the diagnosis and management of pregnancy.

Ectopic pregnancies occur when a fertilized egg implants outside the uterus, most commonly in the fallopian tubes. This condition can lead to serious complications, including rupture of the tube, which can cause internal bleeding and may require emergency surgery. The management of ectopic pregnancies can vary based on the patient's condition, the location of the ectopic tissue, and the stability of the patient.

In cases where the ectopic pregnancy is diagnosed early and the patient is stable, medication such as Methotrexate can be used. Methotrexate is a chemotherapy agent that inhibits cell division and is effective in terminating nonviable pregnancies, including ectopic ones. It works by stopping the growth of rapidly dividing cells, which includes the cells of the embryo. This medication is typically administered as an injection and is most effective when the hCG levels are below a certain threshold (usually less than 5000 mIU/mL). It is important to monitor hCG levels after administration to ensure that they are decreasing, indicating that the treatment is effective.

In your case, since your hCG levels have been fluctuating and have not shown a consistent decline, it raises concerns about the viability of the pregnancy and the potential for complications. If the embryo is nonviable and the hCG levels are decreasing, your doctor may choose to monitor the situation closely, as some ectopic pregnancies can resolve on their own without intervention. However, if there is a risk of rupture or if the hCG levels do not decline appropriately, surgical intervention may be necessary.

Regarding your concerns about the potential for a ruptured fallopian tube, it is valid to be cautious. Symptoms such as severe abdominal pain, dizziness, or fainting should prompt immediate medical attention, as these could indicate a rupture. If you experience these symptoms, it is crucial to seek emergency care.

As for your question about whether you need to take medication to facilitate the expulsion of the nonviable embryo, it depends on the clinical scenario. If the ectopic tissue is stable and there is no immediate risk of rupture, your doctor may opt for a watchful waiting approach. However, if there is a concern about the potential for complications, they may recommend Methotrexate or surgical intervention.

In the event that the ectopic pregnancy resolves on its own, you may not need to follow a specific post-miscarriage care regimen, such as a "miscarriage diet." However, it is essential to follow your doctor's advice regarding follow-up appointments and monitoring your hCG levels until they return to zero.

In summary, the management of ectopic pregnancies requires careful consideration of the patient's clinical status and the risks involved. It is essential to maintain open communication with your healthcare provider, express your concerns, and ensure that you understand the rationale behind the chosen management strategy. If you feel uncertain or anxious about your treatment plan, do not hesitate to seek a second opinion or ask for further clarification from your doctor. Your health and peace of mind are paramount during this challenging time.

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