Managing Anxiety and Depression Medication: Addressing Withdrawal and Side Effects - Psychiatry

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Issues with Discontinuing Medication for Anxiety and Depression


Hello, Doctor.
I have been diagnosed with anxiety, panic disorder, depression, and sleep disturbances.
Currently, I am taking medication: one capsule of Yongkangxu and one capsule of Anning in the morning and evening, and half a capsule of Daomei before bed, along with 0.5 mg of Rifuqian, which I have been taking for almost three months.
The doctor suggested that I stop taking the Anning capsule at night, but after stopping it for two days, my anxiety increased significantly during the night for two consecutive days.
I had to go to the emergency department at Yadong to receive an injection of Midazolam before I could sleep at home.
I discussed this with my attending physician, who advised me to resume taking the Anning capsule as before.
However, I often experience heightened anxiety between 8 PM and 10 PM.
I am unsure if the medication concentration is still insufficient or if it is a psychological issue.
Additionally, I have been eating regular meals but am constantly worried about the side effects of Yongkangxu, particularly constipation.
How can I alleviate my constipation? Can I go to a general clinic to get a prescription for a laxative? Thank you, Doctor.

Mr. Lin, 40~49 year old female. Ask Date: 2020/07/02

Dr. Wu Enliang reply Psychiatry


Hello, netizen:
Q1: I experience heightened anxiety mostly between 8 to 10 PM.
I'm not sure if it's due to insufficient medication levels or if it's a psychological issue.

A: The tranquilizer capsule is a sedative, and taking it continuously for three months may lead to physical dependence.
Stopping suddenly can indeed cause rebound anxiety.
I recommend discussing your medication with your physician or considering non-pharmacological relaxation methods, such as biofeedback training.
Q2: I maintain a normal diet for all three meals, yet I am constantly worried about the side effects of Yongkangxu, particularly constipation.
What can I do to alleviate constipation? Can I go to a general clinic to get a laxative prescription?
A: The general principles for alleviating constipation include increasing fiber intake, exercising more, and drinking plenty of water.
If constipation persists, you may need to consider changing your medication.
If necessary, you can request a laxative from your psychiatrist.

Dr.
Wu Enliang

Reply Date: 2020/07/02

More Info


Managing anxiety and depression, especially when it involves medication, can be a complex process. It's important to understand both the potential side effects of the medications you're taking and how to manage withdrawal symptoms when adjusting your regimen. Based on your description, you are currently taking medications for anxiety, panic, and depression, including 永康緒 (Yongkangxu), 安寧膠囊 (Anning capsule), and 導美睡 (Daomeisleep), along with 利福全 (Rifuqian).
Firstly, it’s crucial to recognize that medications for anxiety and depression can have varying effects on individuals. The side effects you are experiencing, such as increased anxiety after stopping 安寧膠囊, are not uncommon. Many medications, especially those affecting the central nervous system, can lead to withdrawal symptoms when discontinued abruptly. This can include heightened anxiety, insomnia, and other physical symptoms. Your experience of needing to go to the emergency room for anxiety relief indicates that your body may be reacting to the sudden change in your medication regimen.

Your physician's recommendation to resume taking 安寧膠囊 is a prudent one, as it may help stabilize your anxiety levels. It’s essential to communicate openly with your healthcare provider about your symptoms, especially if you notice significant changes in your anxiety levels or any new side effects. Adjusting medication dosages or switching to different medications can sometimes be necessary to find the right balance for your mental health needs.

Regarding your concerns about the side effects of 永康緒, particularly constipation, it’s important to address this issue as it can significantly impact your quality of life. Constipation is a known side effect of many medications, especially those that affect serotonin levels, as they can slow down gastrointestinal motility. To manage constipation, you can consider several strategies:
1. Dietary Changes: Increasing your intake of fiber-rich foods such as fruits, vegetables, whole grains, and legumes can help promote regular bowel movements. Staying well-hydrated by drinking plenty of water is also crucial.

2. Physical Activity: Regular exercise can stimulate bowel function and help alleviate constipation. Even light activities like walking can be beneficial.

3. Over-the-Counter Remedies: If dietary changes and exercise do not help, you may consider using over-the-counter laxatives or stool softeners. It’s advisable to consult with your healthcare provider or a pharmacist before starting any new medication, including laxatives, to ensure they are safe and appropriate for your situation.

4. Consulting a Healthcare Provider: If constipation persists despite these measures, it may be worth discussing with your doctor. They can provide guidance on safe laxatives or possibly adjust your medication regimen if necessary.

As for the increased anxiety you experience in the evenings, this could be related to various factors, including your body's natural circadian rhythms, the timing of your medication, or psychological factors. It might be helpful to establish a calming evening routine, including relaxation techniques such as deep breathing exercises, meditation, or gentle yoga, which can help reduce anxiety levels before bedtime.

In summary, managing anxiety and depression through medication requires careful monitoring and communication with your healthcare provider. Adjustments to your medication should be made under medical supervision, especially if you experience withdrawal symptoms or side effects. Additionally, addressing physical side effects like constipation through lifestyle changes and possibly over-the-counter remedies can improve your overall well-being. Always consult your physician before making any changes to your medication or treatment plan.

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