Chlamydia: Treatment, Testing, and Transmission Concerns - Urology

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Hello doctor, I have been undergoing treatment for Chlamydia for two years, and my IgA and IgG levels are still above 1.1.
The doctor said that after finishing a week of medication, I don't need to return for blood tests, as the pathogens will gradually resolve on their own.
However, my levels remain between 1.2 and 1.8.
If I have Chlamydia, but my boyfriend tested negative, is that possible? Can gonorrhea be detected through a cervical smear test? Thank you!

Xiao Xiao, 30~39 year old female. Ask Date: 2020/07/02

Dr. Cai Zhuorong reply Urology


1.
Testing for Chlamydia using antibody tests is not standard; if there are concerns, consider undergoing Chlamydia PCR testing.

2.
If I have Chlamydia, but my boyfriend tests negative, is this possible? A: Yes, it is possible.

3.
Can gonorrhea be detected through a cervical smear test? A: It is recommended to have a gynecologist perform a smear test and bacterial culture for gonorrhea.

Reply Date: 2020/07/02

More Info


Chlamydia, a common sexually transmitted infection (STI), is caused by the bacterium Chlamydia trachomatis. Understanding its treatment, testing, and transmission is crucial for effective management and prevention.

Treatment
Chlamydia is typically treated with antibiotics. The most commonly prescribed medications include azithromycin (a single dose) or doxycycline (taken for seven days). It's essential to complete the full course of antibiotics to ensure the infection is eradicated. In your case, if you have been treated for two years and your IgA and IgG levels remain elevated (between 1.2 and 1.8), it may indicate a persistent infection or a past infection that your body is still responding to. However, your doctor has indicated that after a week of treatment, further blood tests may not be necessary as the body can often clear the infection on its own over time.

Testing
Testing for chlamydia typically involves a urine test or a swab from the affected area (cervix, urethra, or rectum). The presence of antibodies (IgA and IgG) can indicate past or ongoing infections, but they are not definitive for active infections. If your boyfriend tested negative, it is possible that he either did not contract the infection or that he was not tested during the window period when the infection could have been present. Chlamydia can sometimes be asymptomatic, meaning individuals may not show symptoms even if they are infected.


Transmission Concerns
Chlamydia is primarily transmitted through sexual contact, including vaginal, anal, and oral sex. It is possible for one partner to be infected while the other is not, especially if the infected partner has had a previous infection that was treated or if the infection is in a dormant state. This could explain why you have elevated antibody levels while your boyfriend does not show signs of infection.

Gonorrhea Testing
Regarding gonorrhea, it can indeed be detected through a cervical swab or urine test. If you are concerned about potential co-infection with gonorrhea, it is advisable to discuss this with your healthcare provider. They may recommend testing for both chlamydia and gonorrhea, especially if you have symptoms or if there is a risk of exposure.


Conclusion
In summary, while your elevated IgA and IgG levels indicate a response to chlamydia, it does not necessarily mean you have an active infection. The absence of infection in your boyfriend is possible, and testing for gonorrhea can be done through a cervical swab. It is essential to maintain open communication with your healthcare provider about your concerns and follow their recommendations for testing and treatment. Regular screenings for STIs are crucial for sexually active individuals, especially when there are concerns about potential infections.

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