Congenital Syphilis: Key Questions and Concerns Addressed - Dermatology

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Syphilis


Dear Dr.
Jin,
First of all, thank you for taking the time to respond.
I am a congenital syphilis patient (transmitted from my mother).
I was surprised to discover I had this disease when I donated blood during my military service.
After my discharge, I underwent a two-year course of penicillin treatment at the Taipei STD Prevention Center, but due to the nurses' sarcastic remarks at that center, I just wanted to finish the treatment quickly.
Therefore, I have some unresolved questions in my mind.
I would like to ask you:
1.
Will this disease always be detectable through blood tests even after treatment?
2.
Is there a high likelihood of transmission to the next generation during the process of childbirth? Or should I avoid having children?
3.
Is saliva during kissing also a potential route of transmission?
4.
What precautions should I take in my daily life?
Thank you.

Yu Feng, 30~39 year old female. Ask Date: 2000/12/09

Dr. Jin Lianchun reply Dermatology


In patients with syphilis, if the infection is discovered long after it has occurred, approximately 45% will have a negative VDRL blood test within five years after treatment, while 55% will remain VDRL positive for life.
If treatment is successful, there will be no infectiousness.
How can we determine if the treatment was successful? (1) The VDRL level drops to less than four times the pre-treatment level within one year after treatment.
(2) The VDRL test changes from positive to negative.
(3) The VDRL test remains consistently low positive between two years after treatment.
If treatment is successful, the patient will not be infectious and only needs to be monitored approximately once a year for any reinfection.
Wishing you a speedy recovery!

Reply Date: 2000/12/09

More Info


Congenital syphilis is a serious condition that arises when a mother with syphilis transmits the infection to her baby during pregnancy. Understanding this condition is crucial for both the affected individuals and their families. Below, I will address your key questions and concerns regarding congenital syphilis.

1. Will the disease always show up in blood tests even after treatment?
After appropriate treatment for syphilis, particularly with penicillin, the infection can be effectively cured. However, it is important to note that certain blood tests, such as the non-treponemal tests (e.g., RPR or VDRL), may remain positive for a long time, even after successful treatment. This is due to the presence of antibodies that the body produces in response to the infection. In many cases, these tests may eventually become negative, but this can take time. Treponemal tests, which detect antibodies specific to the syphilis bacterium, may remain positive for life, indicating past infection rather than active disease. Therefore, while treatment can cure the infection, the blood tests may not always reflect this cure immediately.

2. Is there a high risk of transmission to the next generation during childbirth?
Congenital syphilis can occur if a mother is infected during pregnancy, particularly if the infection is not treated. If you have been treated and are no longer infected, the risk of transmission to your child is significantly reduced. However, if there is any uncertainty about your infection status, it is crucial to consult with a healthcare provider before considering pregnancy. Regular prenatal care and screening for syphilis during pregnancy are essential to prevent transmission to the baby. If you are planning to conceive, discussing your health history and any concerns with your healthcare provider is vital.

3. Can kissing transmit the infection?
Syphilis is primarily transmitted through direct contact with syphilitic sores during sexual activity. While it is theoretically possible for syphilis to be transmitted through kissing if there are active sores in the mouth or on the lips, this is considered a rare mode of transmission. The primary concern for transmission remains sexual contact. It is important to practice safe sex and avoid intimate contact if you or your partner have any sores or signs of syphilis.

4. What precautions should be taken in daily life?
Individuals with a history of syphilis should take several precautions to maintain their health and prevent potential transmission. These include:
- Regular medical check-ups: Regular follow-ups with a healthcare provider are essential to monitor your health and ensure that any potential issues are addressed promptly.

- Safe sexual practices: Using condoms and engaging in safe sex practices can help reduce the risk of transmitting syphilis and other sexually transmitted infections (STIs).

- Open communication: It is important to communicate openly with sexual partners about your health history and any concerns regarding STIs.

- Mental health support: Dealing with a chronic condition can be emotionally taxing. Seeking support from mental health professionals or support groups can be beneficial.

In conclusion, congenital syphilis is a serious condition that requires careful management and understanding. If you have further questions or concerns, it is advisable to consult with a healthcare provider who specializes in infectious diseases or sexual health. They can provide personalized guidance based on your specific situation and health history.

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