Post-Prostatectomy Care: Hormone Therapy Options Explained - Urology

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Post-prostatectomy


Hello Dr.
Lee, my father has undergone a Da Vinci prostatectomy over six months ago and is currently under regular follow-up.
I would like to ask you, after prostate removal, is it still necessary to regularly administer hormone blockers? If injections are not given, are there any alternative oral medications available?

Mr. Lin, 40~49 year old female. Ask Date: 2020/07/07

Dr. Li Minghui reply Urology


After a robotic-assisted laparoscopic prostatectomy, the need for additional treatment is generally determined based on the pathology report.
It is advisable to consult with the original treating physician to discuss subsequent treatment options.

Reply Date: 2020/07/07

More Info


After a prostatectomy, particularly following a Da Vinci robotic-assisted surgery, the need for hormone therapy largely depends on the individual patient's pathology report and overall health status. In cases of prostate cancer, hormone therapy, also known as androgen deprivation therapy (ADT), is often considered to reduce the levels of male hormones, such as testosterone, that can fuel the growth of prostate cancer cells.
In your father's case, since he has undergone surgery and is being monitored regularly, the decision to initiate or continue hormone therapy should be based on several factors, including the stage and grade of the cancer, the presence of residual cancer cells, and the patient's PSA (Prostate-Specific Antigen) levels post-surgery. If the pathology report indicates that the cancer was localized and fully removed, and if the PSA levels are stable and low, the need for ongoing hormone therapy may be less critical. However, if there are indications of aggressive cancer or rising PSA levels, hormone therapy might be recommended to prevent recurrence.

Regarding alternatives to injectable hormone therapy, there are indeed oral medications available. For instance, medications such as enzalutamide and abiraterone are oral options that can be used to manage prostate cancer by inhibiting androgen receptors or blocking androgen production, respectively. These medications are typically used in advanced cases or when the cancer has metastasized, but they may also be considered in certain situations post-surgery.

It's essential for your father to have a thorough discussion with his oncologist or urologist about the potential benefits and risks of continuing hormone therapy versus exploring alternative medications. The healthcare provider can offer personalized recommendations based on the latest clinical guidelines and your father's specific health profile.

In addition to hormone therapy, post-prostatectomy care may also involve managing side effects such as urinary incontinence and erectile dysfunction, which are common after surgery. Pelvic floor exercises, bladder training, and medications can help alleviate these issues. Regular follow-up appointments are crucial to monitor PSA levels and assess any symptoms or side effects from treatments.

In summary, the decision to continue hormone therapy after prostatectomy should be individualized based on pathology results and PSA levels. There are oral alternatives to injections, and a comprehensive approach to post-surgical care can significantly enhance your father's quality of life. Always consult with the treating physician for the most appropriate course of action tailored to your father's needs.

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