Syphilis Test Results: What Do Positive PRP and Negative CIA/TPHA Mean? - Urology

More Info

---

Understanding syphilis test results can be quite complex, especially when interpreting the implications of various tests such as the Rapid Plasma Reagin (RPR) and Treponema pallidum hemagglutination assay (TPHA). In your case, the results show a positive RPR and negative TPHA on two separate occasions, which raises several important questions regarding syphilis diagnosis and potential implications for you and your partner.


Interpretation of Test Results
1. Positive RPR (1x+): The RPR test is a non-treponemal test used for screening syphilis. A positive result indicates that there may be an active infection or a past infection, but it is not specific to syphilis. False positives can occur due to various reasons, including other infections, autoimmune diseases, or even pregnancy.

2. Negative TPHA (<0.10): The TPHA test is a treponemal test that detects antibodies specific to Treponema pallidum, the bacterium that causes syphilis. A negative TPHA result suggests that there is no evidence of a current or past syphilis infection.

Conclusion from Results
Given that you have two positive RPR results but negative TPHA results, this combination is suggestive of a false positive RPR. It is important to note that the RPR can remain positive for some time even after successful treatment of syphilis, but in your case, the negative TPHA indicates that there is no confirmed syphilis infection. Therefore, you are not diagnosed with syphilis, nor are you considered a carrier of the disease.


Frequent Headaches and Their Relation
Regarding your frequent headaches, they are unlikely to be related to syphilis, especially given the negative TPHA results. However, if you are experiencing persistent headaches, it is advisable to consult a healthcare professional to explore other potential causes, which could range from tension headaches to more serious underlying conditions.


Partner Considerations
Since your test results do not indicate an active syphilis infection, your partner does not need to be concerned about syphilis transmission based on these results. However, it is always a good practice for sexually active individuals to undergo regular STI screenings, especially if there are any symptoms or concerns.


Recommendations
1. Follow-Up Testing: It is advisable to consult with your healthcare provider for further testing. They may recommend additional tests to confirm the results and rule out any other potential conditions that could cause a positive RPR.

2. Discuss Symptoms: If you continue to experience headaches or any other symptoms, make sure to discuss these with your doctor. They can help determine if further investigation is needed.

3. Regular Screenings: Continue to have regular STI screenings, especially if you have new partners or engage in high-risk behaviors.

4. Communication with Partner: Keep an open line of communication with your partner regarding sexual health and testing. This is crucial for maintaining a healthy relationship.

In summary, your test results suggest that you do not have syphilis, and the positive RPR may be a false positive. It is essential to follow up with your healthcare provider for further evaluation and to address any ongoing symptoms. Regular screenings and open communication with your partner will help ensure both of your health and well-being.