Skin Pigmentation: When to Seek Medical Advice - Dermatology

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Pigmentation deposition


Hello doctor, my husband has a patch of dark pigmentation on both of his knees, with the color extending to the inner and upper parts of the knees.
It is not painful or itchy.
Does he need to undergo further examination?

Yunxuan, 30~39 year old female. Ask Date: 2020/07/11

Dr. Wu Yuxin reply Dermatology


No lesions were observed, and it is not possible to determine the issue.
If you are very concerned, please seek medical attention promptly.

Reply Date: 2020/07/11

More Info


When it comes to skin pigmentation changes, such as the deep pigmentation your husband is experiencing on his knees, it is essential to approach the situation with caution and awareness. Skin pigmentation can be influenced by various factors, including genetics, sun exposure, hormonal changes, and underlying medical conditions.
In your husband's case, the presence of a dark patch on the knees that is not painful or itchy may suggest a few possibilities. One common cause of localized hyperpigmentation is post-inflammatory hyperpigmentation, which can occur after an injury or irritation to the skin. However, since there is no history of trauma or irritation mentioned, other conditions should also be considered.

Another possibility is a condition known as acanthosis nigricans, which is characterized by dark, velvety patches of skin, often found in body folds. This condition can be associated with insulin resistance and other metabolic disorders. Additionally, certain medications, hormonal changes, or even benign skin conditions like lentigines (age spots) could also lead to increased pigmentation.

Given that the pigmentation has persisted and extended to other areas, it would be prudent to seek medical advice. A dermatologist can conduct a thorough examination of the affected area and may perform a skin biopsy if necessary to rule out any serious conditions, such as melanoma or other skin cancers. While the absence of pain or itching is a positive sign, it does not eliminate the need for professional evaluation.

In terms of when to seek medical advice regarding skin pigmentation changes, consider the following guidelines:
1. Duration: If the pigmentation has been present for more than a few weeks without improvement, it is advisable to consult a dermatologist.

2. Changes in Appearance: If the pigmentation changes in size, shape, or color, or if new symptoms develop (such as itching, pain, or bleeding), it is essential to seek medical attention promptly.

3. Associated Symptoms: If there are any systemic symptoms, such as weight loss, fatigue, or changes in appetite, these could indicate an underlying health issue that requires further investigation.

4. Family History: If there is a family history of skin cancer or other dermatological conditions, it is wise to have any new or changing pigmentation evaluated by a professional.

5. Cosmetic Concerns: If the pigmentation is affecting your husband's self-esteem or quality of life, discussing treatment options with a dermatologist can provide reassurance and potential solutions.

In conclusion, while the pigmentation on your husband’s knees may not currently present any alarming symptoms, it is always better to err on the side of caution when it comes to skin changes. Consulting a dermatologist will provide clarity and peace of mind, ensuring that any necessary treatment or monitoring is initiated. Regular skin checks and awareness of changes in skin appearance are vital components of maintaining skin health.

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