Safe Medication for Pregnant Women: Cold Remedies at 15 Weeks - Obstetrics and Gynecology

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Medication Inquiry for Cold During 15 Weeks of Pregnancy


Hello, I would like to inquire about the following medications for a cold:
1.
POTARLON CAP.
250MG - Active ingredient: Mefenamic Acid
2.
SUCOUGH TABLET 20M - Active ingredient: Benproperine Phosphate
3.
GOWELL TABLET "EVE" - Antacid, gastrointestinal medication
4.
MEQAZINE (5) - Active ingredient: Mequitazine
5.
CIMETIDINE TABLETS - Active ingredient: Cimetidine
6.
REZINON TABLETS 20 - Active ingredient: Eorazinone HCl
I have also checked online and found that a couple of these medications appear to be classified as Category C.
Are these medications suitable for a 15-week pregnant woman? Thank you!

Iris, 20~29 year old female. Ask Date: 2020/07/13

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it generally does not have an impact.
Wishing you good health.

Reply Date: 2020/07/13

More Info


When it comes to treating a cold during pregnancy, especially at 15 weeks, it is crucial to prioritize the safety of both the mother and the developing fetus. The medications you mentioned—POTARLON (Mefenamic Acid), SUCOUGH TABLET (Benproperine Phosphate), GOWELL TABLET "EVE" (antacid), MEQAZINE (Mequitazine), CIMETIDINE TABLETS, and REZINON TABLETS (Eorazinone HCl)—have varying safety profiles during pregnancy.

1. Mefenamic Acid (POTARLON): This is a non-steroidal anti-inflammatory drug (NSAID) that is generally not recommended during pregnancy, especially in the third trimester, due to potential risks such as premature closure of the ductus arteriosus in the fetus. However, its use in the first and second trimesters should be approached with caution and typically avoided unless absolutely necessary.

2. Benproperine Phosphate (SUCOUGH TABLET): This is a cough suppressant. While there is limited data on its safety during pregnancy, it is generally advisable to avoid medications that are not well-studied in pregnant populations. If the cough is severe, it may be worth discussing alternative treatments with your healthcare provider.

3. Antacids (GOWELL TABLET "EVE"): Antacids are usually considered safe during pregnancy. They can help alleviate heartburn and indigestion, which are common complaints during pregnancy. However, it’s important to choose antacids that do not contain high levels of sodium or certain other ingredients that may not be recommended.

4. Mequitazine (MEQAZINE): This is an antihistamine used for allergies and motion sickness. While some antihistamines are considered safe during pregnancy, others may not be. Mequitazine is classified as a Category C drug, meaning that risk cannot be ruled out. It should only be used if the potential benefits justify the potential risks to the fetus.

5. Cimetidine: This medication is used to treat stomach ulcers and gastroesophageal reflux disease (GERD). It is generally considered safe during pregnancy, but there are other alternatives that may be preferred due to potential side effects.

6. Eorazinone HCl (REZINON TABLETS): The safety profile of this medication is less well-known, and it is advisable to consult with a healthcare provider before using it during pregnancy.

In summary, while some of these medications may be used with caution, it is essential to consult with a healthcare provider who can evaluate your specific situation and recommend the safest options. Generally, during pregnancy, especially in the first and second trimesters, it is recommended to use medications that are classified as Category A or B, and to avoid those classified as Category C unless absolutely necessary.

Additionally, non-pharmacological approaches to managing cold symptoms can be beneficial. These include staying hydrated, using a humidifier, and getting plenty of rest. If symptoms persist or worsen, it is crucial to seek medical attention. Always discuss any medication use with your healthcare provider to ensure the safety of both you and your baby.

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