the Link Between Nasopharyngeal Cancer and Sinusitis - Otolaryngology

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Nasal cavity and paranasal sinus examination for nasopharyngeal carcinoma and sinusitis?


Hello Doctor, I started experiencing symptoms like coughing in early April without a fever.
Initially, the clinic diagnosed it as a cold, but after taking medication for a month, my cough did not improve, and I also had some headaches.
In early May, I had a chest X-ray, which showed no issues.
It wasn't until early July that I was diagnosed with sinusitis (after undergoing a nasal endoscopy) and was prescribed antibiotics.
I would like to ask the doctor, as I have noticed some blood streaks when blowing my nose and occasionally a bit of blood when coughing up phlegm, along with my grandmother having nasopharyngeal cancer, should I request a CT scan at my next appointment, even if it is out-of-pocket?

Frank, 20~29 year old female. Ask Date: 2020/07/15

Dr. Zheng Jueyi reply Otolaryngology


Hello: Please inform the physician that there is a family history of nasopharyngeal carcinoma, although it has not been confirmed by a CT scan.
It is recommended that the physician conduct a thorough examination of the nasopharynx, and if necessary, a biopsy of the nasopharyngeal area should be performed for definitive diagnosis.
Wishing you peace and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2020/07/15

More Info


When considering the relationship between nasopharyngeal cancer (NPC) and sinusitis, it's essential to understand the distinct characteristics of both conditions, as well as the symptoms that may overlap. Your situation, with a history of sinusitis and a family history of NPC, understandably raises concerns about the possibility of cancer.

Differentiating Sinusitis from Nasopharyngeal Cancer
Sinusitis, or inflammation of the sinus cavities, can present with symptoms such as nasal congestion, facial pain, headache, and sometimes fever. In chronic cases, patients may experience post-nasal drip, which can lead to throat irritation and coughing. The presence of blood in nasal discharge or sputum can occur in sinusitis, particularly if there is significant irritation or inflammation of the nasal mucosa.
On the other hand, nasopharyngeal cancer may present with more specific symptoms, including persistent nasal obstruction, nasal bleeding, ear fullness or pain, and possibly neck swelling due to lymph node involvement. The presence of blood in nasal discharge, especially if it is recurrent or significant, can be concerning and warrants further investigation.

Your Symptoms and Family History
Given your symptoms of persistent cough, occasional blood-streaked nasal discharge, and a family history of NPC, it is prudent to approach your healthcare provider with these concerns. While the presence of blood can be alarming, it is important to note that many cases of sinusitis can lead to minor bleeding due to inflammation and irritation. However, the combination of your symptoms and family history does increase the need for thorough evaluation.

Next Steps: Imaging and Evaluation
Discussing the option of a CT scan with your doctor is a reasonable step. A CT scan can provide detailed images of the sinuses and nasopharynx, helping to identify any abnormalities such as tumors, significant sinus blockage, or other structural issues. Given your ongoing symptoms and the lack of improvement with treatment, this imaging could be beneficial in ruling out more serious conditions, including NPC.

Additionally, if your doctor finds any suspicious lesions during a nasal endoscopy, they may recommend a biopsy to definitively rule out cancer.
Conclusion
In summary, while your symptoms may be consistent with chronic sinusitis, the presence of blood and your family history necessitate a careful evaluation. It is advisable to communicate openly with your healthcare provider about your concerns and the possibility of further imaging. Early detection and diagnosis are crucial in managing any potential health issues effectively. Remember, while it is natural to worry about serious conditions like cancer, many symptoms can be attributed to less severe issues, and a thorough medical evaluation is the best way to gain clarity and peace of mind.

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