Navigating Hepatitis C Treatment: Options, Costs, and Lifestyle Considerations - Gastroenterology and Hepatology

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Hepatitis C treatment


Hello, doctors.
I have been suffering from liver disease for a long time.
Five years ago, a blood test revealed that I had both hepatitis B and C viruses.
A month later, I went to a Christian hospital for further testing, and it confirmed only hepatitis C.
Since then, I have been undergoing follow-up treatment, and it has consistently shown only hepatitis C.
My GOT and GPT levels have been slightly elevated, ranging from 60 to 70, and have not returned to normal.
In my most recent ultrasound examination, the doctor informed me that I have moderate fibrosis and slightly low platelet counts.
They recommended interferon treatment; however, I am currently in graduate school and facing financial difficulties.
I am concerned that I may not be able to afford the treatment or its side effects over the course of a year and a half.
I told the doctor that I would like to postpone it for now and continue taking medication, specifically Hepatoprotective agents, without further treatment.
I am unsure how to make a decision.
I don't know if I should immediately start interferon treatment.
What is the treatment success rate? What should I pay attention to in my daily life? I want to live happily.
I try to stay positive, but my liver disease has led me to visit a psychiatrist multiple times.
A major concern is my fear of transmitting the virus to others and the numerous possibilities of transmission.
Even when I have mouth sores, I avoid eating out.
My physical condition is deteriorating, although my appetite is decent.
I have become quite thin and have not gained any weight.
I suspect my digestive function is affected by my liver disease.
I am quite introverted but very motivated; however, I have never been satisfied with my physical condition.
This is largely due to the lack of medical resources in my hometown during my childhood and the ignorance of hygiene concepts among adults.
I hope to reach the day I aspire to.
Thank you for your hard work.

Xihuan Daziran de Yiqie, 20~29 year old female. Ask Date: 2003/01/02

Dr. Yang Peizhen reply Gastroenterology and Hepatology


Hello! First of all, it must be emphasized that hepatitis C is transmitted through blood and bodily fluids, and is fundamentally unrelated to diet.
Chronic hepatitis C has a high rate of viral mutation, which makes treatment outcomes less than ideal.
Currently, the most effective treatment regimen is a combination of long-acting interferon and oral ribavirin for six consecutive months, with a cure rate of about 50%.
However, the cost is quite high, amounting to nearly NT$200,000 to NT$300,000.
The side effects are relatively mild, but may still include decreases in white blood cells, platelets, and hemoglobin.
As for daily maintenance, a light and balanced diet, sufficient sleep, and avoiding the indiscriminate use of over-the-counter medications or folk remedies are recommended, allowing you to lead a colorful life.
Best wishes for your health from Dr.
Yang Pei-Chen, Gastroenterology Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/01/02

More Info


Navigating the treatment of Hepatitis C can be a complex journey, especially when considering the financial implications, treatment options, and lifestyle adjustments necessary for managing the condition. Given your situation, where you have been diagnosed with Hepatitis C and are experiencing moderate fibrosis, it’s crucial to weigh your options carefully.


Treatment Options
The primary treatment for Hepatitis C has evolved significantly over the years. Currently, the most effective treatment involves direct-acting antiviral (DAA) medications, which can cure the infection in most cases. These medications are typically taken orally for 8 to 12 weeks, depending on the specific drug regimen and the genotype of the virus. The cure rates for DAAs can exceed 95%, making them a highly effective option.

In your case, the recommendation for interferon therapy may be based on your specific health circumstances, including the degree of liver fibrosis and your overall health. Interferon, particularly when combined with ribavirin, has been used in the past, but it is less favored now due to the side effects and lower efficacy compared to DAAs. The treatment duration for interferon can be longer, often requiring 24 to 48 weeks, and it can come with significant side effects, including flu-like symptoms, fatigue, and potential impacts on mental health.


Costs and Financial Considerations
The cost of Hepatitis C treatment can vary widely depending on the medication prescribed and whether you have insurance coverage. In many countries, including the United States, DAAs can be expensive, often ranging from $20,000 to $100,000 for a full course of treatment. However, many insurance plans cover these medications, and there may be financial assistance programs available through pharmaceutical companies or non-profit organizations.

In your case, if you are concerned about the cost of treatment, it may be beneficial to discuss this with your healthcare provider. They can help you explore options for financial assistance or alternative treatment plans that may be more affordable.


Lifestyle Adjustments
Living with Hepatitis C, especially with moderate fibrosis, requires some lifestyle adjustments to support liver health. Here are some recommendations:
1. Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid alcohol, as it can exacerbate liver damage. Staying hydrated is also essential.

2. Regular Check-ups: Regular monitoring of liver function tests (like ALT and AST) and imaging studies (like ultrasounds) is crucial to assess the progression of liver disease.

3. Mental Health: Given your concerns about transmission and the emotional toll of living with a chronic illness, it’s important to prioritize mental health. Consider speaking with a mental health professional who can help you manage anxiety and stress related to your condition.

4. Preventing Transmission: Hepatitis C is primarily transmitted through blood-to-blood contact. It’s important to avoid sharing personal items that may have blood on them, such as razors or toothbrushes. Safe practices during sexual activity are also recommended, especially if you have multiple partners.

5. Exercise: Regular physical activity can help improve your overall health and well-being. Aim for at least 150 minutes of moderate aerobic activity each week, as tolerated.


Conclusion
Ultimately, the decision to start treatment should be made in consultation with your healthcare provider, taking into account your specific health status, the potential benefits and risks of treatment, and your financial situation. It’s understandable to feel overwhelmed, but remember that there are resources available to support you through this process. Your health and well-being are paramount, and taking proactive steps can lead you toward a healthier future.

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