Ventricular Premature Contractions: Treatment Options and Concerns - Cardiology

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Hello, doctor. I would like to ask about the issue of premature ventricular contractions (PVCs)?


Hello Doctor, on the night of March 11th, I suddenly experienced a rapid heartbeat and went to the emergency room.
After that, I visited a cardiologist in April.
The echocardiogram was normal, but the 24-hour Holter monitor showed around 200 ventricular premature contractions (VPCs).
The doctor said medication was not necessary, but I felt uncomfortable, so I consulted again and was prescribed Duzhong (a medication for autonomic nervous system regulation).
After taking it for three days, I felt less palpitations, but on the fourth day, the palpitations returned.
The doctor then prescribed a quarter of a 5mg Betaloc (metoprolol), which initially alleviated the palpitations but caused some dizziness.
After stopping the medication for five days, the sensation of ventricular premature contractions returned.
The doctor switched me to half a 50mg Atenolol, but after reviewing the side effects of Atenolol and the potential chest pain and palpitations from discontinuation, I felt hesitant to take it, as it seems more dangerous than Betaloc.
I would like to ask the doctor whether it is advisable to continue with Duzhong and a quarter of Betaloc or switch to half a Atenolol.
Will I need to be on medication for life, and will my condition worsen? The sudden onset of ventricular premature contractions over the past few months has left me feeling quite helpless.
Thank you for your assistance!

Yang, 20~29 year old female. Ask Date: 2020/08/13

Dr. He Dongjin reply Cardiology


Hello, having around 200 ventricular premature contractions (VPCs) in a 24-hour Holter monitor is within the normal range and does not require medication.
Occasional palpitations are also considered normal.
While symptoms may cause discomfort, there is no life-threatening risk, and you will not need medication for life.
It will not worsen, so there is no need to worry.
It is recommended to take Yuanxu and Baisiao 1/4, but if you feel uncomfortable, you can discontinue it or switch to Inderal 10 mg.
Peace of mind from Changhua Hospital cares about you.

Reply Date: 2020/08/13

More Info


Ventricular premature contractions (VPCs), also known as premature ventricular beats (PVBs), are common arrhythmias characterized by early heartbeats originating from the ventricles. While they can be alarming, especially when experienced as palpitations or a racing heart, they are often benign in individuals without underlying heart disease. However, the presence of frequent VPCs can sometimes indicate a need for further evaluation and management, particularly if they are symptomatic or associated with other cardiac conditions.

In your case, the fact that you experienced a sudden increase in heart rate and were subsequently diagnosed with approximately 200 VPCs over a 24-hour period is noteworthy. The initial assessment, including an echocardiogram, was normal, which is reassuring as it suggests that there are no significant structural heart issues contributing to your symptoms. The management of VPCs often depends on the frequency of the contractions, the presence of symptoms, and any underlying heart conditions.

Your doctor’s recommendation to avoid medication in the absence of significant symptoms is consistent with current guidelines. Many patients with infrequent VPCs do not require treatment. However, since you have been experiencing discomfort and palpitations, your physician has appropriately considered pharmacological options. The medications you mentioned, including Dronedarone (得原緒) and Bisoprolol (百適歐), are used to manage arrhythmias and can help alleviate symptoms.

Dronedarone is an antiarrhythmic medication that can help control heart rhythm and is generally well-tolerated. However, it is essential to monitor for any side effects, especially in patients with pre-existing conditions. Bisoprolol, a beta-blocker, is often prescribed to manage symptoms related to anxiety and palpitations, and it can also help reduce the frequency of VPCs. While you experienced dizziness with Bisoprolol, it is crucial to communicate this with your doctor, as they may need to adjust the dosage or consider alternative medications.

Regarding your concerns about long-term medication use, it is not uncommon for patients with VPCs to require ongoing treatment, particularly if they experience significant symptoms. However, many patients can manage their symptoms with lifestyle modifications, such as reducing caffeine intake, managing stress, and avoiding stimulants. Regular follow-up with your cardiologist is essential to monitor your condition and adjust treatment as necessary.

It is also important to note that while VPCs can be bothersome, they do not typically lead to more severe arrhythmias or heart disease in individuals without underlying cardiac issues. However, if you notice an increase in the frequency of VPCs, or if they become more symptomatic, further evaluation may be warranted. This could include additional monitoring, such as a Holter monitor, or even an electrophysiological study if indicated.

In conclusion, your management plan should be tailored to your specific symptoms and response to medications. It is advisable to have an open discussion with your cardiologist about your concerns regarding the side effects of medications and the potential need for long-term treatment. They can help you weigh the benefits and risks of each medication and determine the best approach for your situation. Remember, the goal is to improve your quality of life while ensuring your heart health remains stable.

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