Drug Allergies: Symptoms and When to Seek Help - Family Medicine

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Drug allergy issues


Hello Doctor, I visited the doctor this Thursday due to back pain and was prescribed Voren EMC Cap 50mg, an anti-inflammatory medication.
After taking two capsules, I noticed a sore at the base of my tongue and experienced throat pain when eating (though I'm not sure if it's related since it's close to the base; swallowing saliva doesn't hurt).
After noticing this, I stopped taking the medication last night.
This morning, I woke up to find a sore on my hand, and I'm unsure if it's related.
The body hasn't developed any rashes, but the medication packaging mentioned that if experiencing throat pain, oral ulcers, or rashes, I should stop the medication and seek medical attention.
I consulted a clinic, and they said it was fine, but I'm still a bit worried.
I would like to ask the doctor if this could be a drug allergy? Will it resolve on its own after stopping the medication?

Huang, 20~29 year old female. Ask Date: 2020/08/15

Dr. Wu Zongying reply Family Medicine


Hello: Anti-inflammatory and analgesic medications can indeed cause allergic reactions in some users.
Most commonly, individuals may experience urticaria, characterized by redness, swelling, and itching of the skin.
In more severe cases, it can lead to mucosal blistering, mucosal erosion, widespread skin detachment, necrosis, and fever, which is medically referred to as Stevens-Johnson Syndrome.
Based on the photo you provided, it appears that there is only skin abrasion on the fingers and a sore throat, which does not seem to indicate Stevens-Johnson Syndrome.
However, if the skin and mucosal symptoms worsen, it is important to consider Stevens-Johnson Syndrome and seek immediate medical attention.

Reply Date: 2020/08/15

More Info


Understanding drug allergies is crucial for ensuring patient safety and effective treatment. Drug allergies can manifest in various ways, and recognizing the symptoms is essential for timely intervention. In your case, you have experienced some concerning symptoms after taking Voren (diclofenac), which is a non-steroidal anti-inflammatory drug (NSAID).

Symptoms of Drug Allergies
Common symptoms of drug allergies can include:
1. Skin Reactions: This may involve rashes, hives, or other forms of skin irritation.

2. Respiratory Issues: Difficulty breathing, wheezing, or throat tightness can indicate a serious allergic reaction.

3. Gastrointestinal Symptoms: Nausea, vomiting, or diarrhea may occur.

4. Oral Symptoms: Swelling of the lips, tongue, or throat, and oral ulcers or sores can be signs of an allergic reaction.

5. Anaphylaxis: This is a severe, life-threatening allergic reaction that requires immediate medical attention. Symptoms include swelling of the throat, difficulty breathing, rapid pulse, and loss of consciousness.

In your situation, the development of a sore at the base of your tongue and the sensation of throat pain after taking Voren raises some concerns. While these symptoms could be related to the medication, they may also be indicative of a non-allergic side effect, such as irritation or ulceration, which can occur with NSAIDs.


When to Seek Help
You should seek medical attention if you experience any of the following:
- Severe Symptoms: If you have difficulty breathing, swelling of the face or throat, or a rapid heartbeat, you should seek emergency medical care immediately.

- Persistent Symptoms: If your symptoms do not improve after stopping the medication or worsen over time, it is important to consult a healthcare provider.

- New Symptoms: If you develop new symptoms, such as a rash or fever, after taking the medication, this could indicate a more serious reaction.


Your Current Situation
Based on your description, it is prudent to stop taking Voren, especially since you have developed symptoms that could be related to the medication. The fact that you have a sore at the base of your tongue and are experiencing throat pain suggests that your body may be reacting negatively to the drug.
While you mentioned that a clinic advised you that it was "okay," it is essential to trust your instincts. If you feel that your symptoms are concerning, it is always best to seek a second opinion or return to your healthcare provider for further evaluation.

Recovery and Next Steps
In many cases, symptoms related to drug reactions may resolve on their own after discontinuing the offending medication. However, it is crucial to monitor your symptoms closely. If the sore in your mouth or throat pain persists, or if you develop any new symptoms, you should seek medical advice.
Additionally, consider discussing alternative pain management options with your healthcare provider. There are various medications available that may not carry the same risk of adverse effects for you.
In summary, while your symptoms may not definitively indicate a drug allergy, they warrant caution. Stopping the medication was a wise decision, and monitoring your symptoms will help determine if further medical intervention is necessary. Always prioritize your health and well-being, and do not hesitate to seek help when in doubt.

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