Could Your Blood Test Results Indicate a Blood Disorder? - Oncology

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Could a blood cell report indicate a blood-related disease?


Dear Doctor: I would like to ask for your interpretation of my health check report for this year.
In the past few years, the CBC/DC section only showed an issue with elevated platelet counts (without further examination at the hospital), but this year, my blood test revealed a decrease in Hb as well.
Does this indicate a potential blood-related disease, or could it simply be an issue related to the immune system? Here are my results: Hb: 11.7, RBC: 3.82, WBC: 11,000, PLT: 419, HCT: 35.2, MCV: 92.3, MCH: 30.7.
Neutrophils: 77.8, Lymphocytes: 14.9, Monocytes: 5.2, Eosinophils: 1.9, Basophils: 0.2.

lala, 30~39 year old female. Ask Date: 2020/08/17

Dr. Chen Yunfang reply Oncology


Hello: Not all numbers are normal; some may be elevated or decreased.
However, whether treatment is necessary requires a personal medical consultation to assess if the individual is experiencing discomfort or has a history of illness.
Does this qualify as a blood disorder? It is difficult to determine how each doctor defines the tolerance for disease! Thank you.

Reply Date: 2020/08/17

More Info


Based on the blood test results you provided, there are several indicators that warrant further investigation, particularly concerning potential blood disorders. Let's break down the key components of your Complete Blood Count (CBC) and discuss their implications.

1. Hemoglobin (Hb): Your hemoglobin level is reported at 11.7 g/dL. While this is below the normal range for adult males (typically 13.8 to 17.2 g/dL) and females (12.1 to 15.1 g/dL), it is essential to consider the context. A decrease in hemoglobin can indicate anemia, which can arise from various causes, including nutritional deficiencies (like iron, vitamin B12, or folate), chronic diseases, or bone marrow disorders.

2. Red Blood Cell Count (RBC): Your RBC count is 3.82 million cells/µL, which is also on the lower side of the normal range (4.7 to 6.1 million cells/µL for males and 4.2 to 5.4 million cells/µL for females). This aligns with the low hemoglobin level and suggests that you may be experiencing some form of anemia.

3. White Blood Cell Count (WBC): Your WBC count is elevated at 11,000 cells/µL, which is above the normal range (typically 4,500 to 11,000 cells/µL). An elevated WBC count can indicate an infection, inflammation, or, in some cases, a hematological disorder such as leukemia. The differential count shows a high percentage of neutrophils (77.8%), which often suggests a response to infection or inflammation.

4. Platelet Count (PLT): Your platelet count is 419,000 cells/µL, which is within the normal range (150,000 to 450,000 cells/µL). However, you mentioned a history of thrombocytosis (high platelet count), which can be associated with various conditions, including inflammation, iron deficiency, or myeloproliferative disorders.

5. Hematocrit (HCT): Your hematocrit level is 35.2%, which is slightly below the normal range for females (typically 36% to 46%) and on the lower side for males (41% to 50%). This further supports the indication of anemia.

6. Mean Corpuscular Volume (MCV): Your MCV is 92.3 fL, which is within the normal range (80 to 100 fL). This indicates that the average size of your red blood cells is normal, which can help differentiate between types of anemia.

7. Differential Count: The breakdown of your white blood cells shows a predominance of neutrophils, with lymphocytes at 14.9%, monocytes at 5.2%, eosinophils at 1.9%, and basophils at 0.2%. The elevated neutrophil count could suggest a response to an acute infection or stress, while the relatively low lymphocyte count may indicate a reactive process or stress response.


Conclusion and Recommendations
Given the combination of low hemoglobin and RBC counts, elevated WBC count, and the history of high platelet counts, it is crucial to consider further evaluation. While these results could be indicative of a simple immune response or a transient condition, they could also point to underlying hematological disorders, including various types of anemia or even more serious conditions like myelodysplastic syndromes or leukemias.

I recommend that you consult a hematologist for a comprehensive evaluation. They may suggest additional tests, such as iron studies, vitamin B12 and folate levels, reticulocyte count, and possibly a bone marrow biopsy if indicated. Early diagnosis and intervention are key to managing any potential blood disorders effectively. Additionally, maintaining a balanced diet rich in iron and vitamins, staying hydrated, and managing any underlying health conditions can also support your overall health.

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