Autonomic Nervous System Disorders: Heart Palpitations and Medications - Cardiology

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Is it autonomic nervous system dysfunction?


Hello Doctor, this is Mr.
Yu, inquiry number 159498.
I still have some questions to ask.
1) Does taking propranolol and sertraline have any impact on the liver? 2) Recently, I sometimes experience a brief (one to two seconds) feeling of palpitations or discomfort when changing positions; is this normal or could it indicate autonomic nervous system dysfunction? 3) I came across a condition online called "cardiac neurosis"; is it similar to or the same as autonomic nervous system dysfunction? Thank you.

Mr. Yu, 30~39 year old female. Ask Date: 2020/08/21

Dr. He Dongjin reply Cardiology


Hello, propranolol and sertraline do not have an impact on the liver.
A brief feeling of palpitations or discomfort is normal and can be classified as cardiac neurosis, which is similar to autonomic nervous system dysregulation.
Changhua Hospital cares about your well-being.

Reply Date: 2020/08/21

More Info


Hello Mr. Yu,
Thank you for reaching out again with your questions regarding autonomic nervous system disorders, heart palpitations, and the medications you are currently taking. I appreciate your proactive approach to understanding your health better. Let’s address your concerns one by one.

1. Effects of Propranolol and Sertraline on the Liver: Propranolol is a beta-blocker commonly used to manage heart conditions, anxiety, and hypertension. It is generally considered safe for the liver, but like any medication, it can have side effects. In rare cases, it may cause liver enzyme elevations, so regular monitoring is advisable if you have pre-existing liver conditions. Sertraline, an SSRI (selective serotonin reuptake inhibitor) used primarily for depression and anxiety, is also typically safe for the liver. However, both medications can interact with other substances that affect liver metabolism. If you have concerns about liver health, it’s essential to discuss them with your healthcare provider, who may recommend liver function tests to ensure everything is functioning properly.

2. Transient Palpitations with Position Changes: Experiencing brief episodes of heart palpitations when changing positions can be common and is often related to autonomic nervous system regulation. The autonomic nervous system controls involuntary bodily functions, including heart rate and blood pressure. When you change positions, your body must quickly adjust to maintain blood flow and pressure, which can sometimes lead to sensations of palpitations or discomfort. However, if these episodes are frequent or accompanied by other symptoms like dizziness, chest pain, or shortness of breath, it would be wise to consult your healthcare provider for further evaluation. They may recommend tests such as an ECG or a Holter monitor to assess your heart's activity during these episodes.

3. Cardiac Neurosis vs. Autonomic Nervous System Disorders: "Cardiac neurosis," often referred to as "heart neurosis" or "cardiac anxiety," is a term that describes anxiety related to heart symptoms, including palpitations, chest pain, and fear of heart disease. This condition is closely related to autonomic nervous system disorders, as both involve the interplay between psychological factors and physical symptoms. Individuals with autonomic nervous system disorders may experience heightened sensitivity to bodily sensations, leading to increased anxiety about their heart health. It’s essential to understand that while these terms may describe overlapping symptoms, they are not identical. Cardiac neurosis is more about the psychological response to perceived heart issues, while autonomic nervous system disorders encompass a broader range of physiological dysregulation.

In summary, your concerns about the medications and their effects on your liver are valid, and it’s crucial to maintain open communication with your healthcare provider regarding any side effects or new symptoms you experience. The transient palpitations you mentioned could be a normal response to position changes, but if they persist or worsen, further investigation may be warranted. Lastly, understanding the relationship between cardiac neurosis and autonomic nervous system disorders can help you navigate your symptoms more effectively.

If you have any more questions or need further clarification, please don’t hesitate to reach out. Your health and peace of mind are important, and I wish you all the best on your journey to better understanding and managing your condition.

Take care!

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