Lupus: Should I Be Concerned About New Skin Issues During Pregnancy? - Dermatology

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Immune system


Hello doctor, I was diagnosed with lupus erythematosus when I was young and have been under regular follow-up.
Now that I am married and have moved, I found a rheumatologist who continued my care.
He drew blood and said he didn't see those markers anymore and that I don't need to come back unless there are issues.
I am currently pregnant and suddenly developed a lot of sweat blisters.
I would like to know if this is related to my lupus erythematosus.
Should I return for a follow-up?

Peipei, 20~29 year old female. Ask Date: 2020/09/04

Dr. Li Yufen reply Dermatology


Hello: Dyshidrotic eczema and erythematosus lupus are not necessarily directly related, but the changes in the body during pregnancy and the development of the fetus throughout the pregnancy may require good collaboration between obstetricians and rheumatologists.
Thank you!

Reply Date: 2020/09/04

More Info


When it comes to managing skin issues during pregnancy, especially for someone with a history of lupus (systemic lupus erythematosus, SLE), it is essential to approach the situation with caution and awareness of both the underlying condition and the changes that occur during pregnancy.

Lupus is an autoimmune disease that can affect various systems in the body, including the skin. Pregnant women with lupus may experience changes in their symptoms due to hormonal fluctuations and the immune system's adaptation during pregnancy. While some women may find that their lupus symptoms improve during pregnancy, others may experience flare-ups or new skin issues, such as rashes or lesions.

The appearance of sweat blisters, or vesicular lesions, could be related to several factors. It is important to consider whether these skin changes are a direct manifestation of lupus or if they are due to other pregnancy-related skin conditions. For instance, pregnancy can lead to conditions like pruritic urticarial papules and plaques of pregnancy (PUPPP), which are characterized by itchy, raised bumps and can be mistaken for other skin issues. Additionally, hormonal changes can lead to increased sensitivity and changes in skin texture, which may also contribute to new skin problems.

Given your history of lupus, it is prudent to consult with your rheumatologist or a dermatologist who is familiar with your medical history. Even if your rheumatologist has indicated that your lupus markers are currently stable, any new skin issues should be evaluated to rule out a lupus flare or other dermatological conditions that may require treatment. Early intervention can help manage symptoms effectively and prevent complications.

In terms of treatment, it is crucial to avoid medications that could be harmful during pregnancy. Many topical treatments, especially those containing steroids, should be used cautiously. While low-potency topical steroids may be safe for short-term use, it is essential to consult your healthcare provider before starting any new medication. Non-steroidal options, such as moisturizers or antihistamines, may be recommended to alleviate itching and discomfort.

Moreover, maintaining a healthy skincare routine is vital. This includes using gentle, non-irritating products, staying hydrated, and protecting your skin from excessive sun exposure, as lupus patients are often photosensitive. Regular follow-ups with your healthcare providers will ensure that both your lupus and any new skin issues are monitored appropriately.

In summary, while new skin issues during pregnancy can be concerning, they may not necessarily be directly related to lupus. However, given your medical history, it is advisable to seek medical advice to ensure that any new symptoms are appropriately evaluated and managed. Your healthcare team can provide guidance tailored to your specific situation, ensuring both your health and the health of your baby are prioritized.

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