Drug interactions
Hello doctor, I have been seeing a neurologist this year and taking autonomic nervous system medications (Erispan-S 0.25mg) and (Propranolol 10mg).
This past month, I was diagnosed with high myopia and glaucoma, and I started using Mikelan LA 2% ophthalmic solution (2.5ml) for about two weeks.
I have experienced severe dizziness, a heavy feeling in my head, headaches, weakness in my calves, and discomfort in my cervical spine.
I would like to ask if these symptoms are caused by an interaction between the two medications? Should I first return to the neurologist for a follow-up or see an ophthalmologist to change my medication? Thank you, doctor, for your time and clarification.
Na Na Jiang, 50~59 year old female. Ask Date: 2020/09/10
Dr. Gao Pilin reply Ophthalmology
Hello Nana: The side effects of Mikelan are minimal.
However, it is a beta-blocker, similar in action to propranolol, and the two medications may cause your discomfort due to their similar effects.
You may want to consult with an ophthalmologist to see if you can switch to a different glaucoma medication.
The ophthalmology department at Puzi Hospital in Taiwan is available on Monday, Tuesday, Thursday, and Friday mornings from 8:00 AM to 12:00 PM, and Wednesday afternoons from 2:00 PM to 4:30 PM.
Please note that online responses are for reference only; it is essential to seek medical attention at a healthcare facility if necessary.
I hope to have the opportunity to assist you.
Gao Pilin
Reply Date: 2020/09/10
More Info
When it comes to understanding drug interactions, especially in the context of ophthalmology and the medications you are currently taking, it is essential to consider how different drugs can affect each other and the body as a whole. You mentioned that you are taking Erispan-S (a medication for autonomic nervous system disorders) and Propranolol (a beta-blocker used for various cardiovascular conditions), along with Mikelan (a glaucoma medication).
Firstly, it is important to note that both Propranolol and Mikelan have similar mechanisms of action as they are both beta-blockers. This overlap can lead to compounded effects, particularly in terms of side effects. The symptoms you are experiencing—severe dizziness, headaches, weakness in your calves, and neck discomfort—could indeed be related to the interaction between these medications. Beta-blockers can lower blood pressure and heart rate, and when combined, they may exacerbate these effects, leading to symptoms like dizziness and weakness.
In terms of managing these symptoms, it is crucial to address them with the appropriate healthcare provider. Since you are experiencing significant side effects, it would be advisable to consult with your neurologist first. They can evaluate whether the symptoms are indeed related to the medications you are taking for your autonomic nervous system condition and whether any adjustments need to be made. After discussing your symptoms with your neurologist, you can then follow up with your ophthalmologist regarding the Mikelan eye drops. They may consider switching you to a different glaucoma medication that does not interact with your current medications or that has a different side effect profile.
In addition to the potential drug interactions, it is also essential to consider your overall health status, including any underlying conditions that may be contributing to your symptoms. For example, if you have a history of low blood pressure or other cardiovascular issues, this could further complicate how these medications interact.
Moreover, it is also worth mentioning that when using eye drops, some systemic absorption can occur, leading to side effects that may not be directly related to the eye condition being treated. This is particularly true for medications like Mikelan, which can have systemic effects due to their pharmacological properties.
In summary, given the complexity of your situation, it is best to first consult with your neurologist to assess the side effects you are experiencing. They can help determine if the medications you are taking are the cause and if any adjustments are necessary. After that, you can follow up with your ophthalmologist to discuss your glaucoma treatment and any potential changes to your eye drops. Always ensure that you communicate all your medications and symptoms to both specialists to facilitate a comprehensive approach to your care.
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