Medications for Passing Calcium Oxalate Kidney Stones - Urology

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Medications for passing kidney stones?


Hello Doctor: I currently have a calcium oxalate kidney stone in my ureter.
It's not large and hasn't caused any pain or hematuria, just a slight feeling of swelling.
Since I am in the United States, I saw a urologist who prescribed me Tamsulosin HCL 0.4 mg and Ketorolac 10 mg.
The latter is likely a pain reliever, so if I am not in pain, I probably don't need to take it, right? The former medication is intended to help with stone passage, correct? Is it similar in effect to the Buscopan I used in Taiwan? Since I have both medications on hand, which one is more suitable for my current condition?

QQQ, 20~29 year old female. Ask Date: 2020/09/15

Dr. Du Shixi reply Urology


Hello: The former is a medication for the prostate, and research suggests it may help with stone passage.
Buscopan is a muscle relaxant that aids in the passage of stones, while ketorolac is a pain reliever.
If you are certain you are not in pain, you may skip it; otherwise, if pain suddenly occurs, you should go to the emergency room.
This facility does not provide consultations and cannot recommend medications; please use the prescriptions provided by your attending physician.
If you have any questions about medications, please consult your doctor.
Wishing you good health.

Reply Date: 2020/09/15

More Info


When dealing with calcium oxalate kidney stones, it's essential to understand the medications prescribed and their roles in managing the condition. In your case, you have been prescribed Tamsulosin HCL and Ketorolac. Let's break down these medications and their relevance to your situation.

Tamsulosin HCL is an alpha-blocker commonly used to treat benign prostatic hyperplasia (BPH) but has also been found to aid in the passage of kidney stones. It works by relaxing the muscles in the bladder and prostate, which can help facilitate the movement of stones through the urinary tract. This medication is particularly beneficial for stones located in the ureter, as it can help reduce the pressure and discomfort associated with their passage.
On the other hand, Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) used primarily for pain relief. It is effective in managing moderate to severe pain, but if you are not experiencing pain, you may not need to take it. However, it is crucial to have it on hand in case you experience sudden discomfort, as kidney stones can sometimes cause acute pain when they move or obstruct the urinary tract.

You mentioned having Buscopan in Taiwan, which is an antispasmodic medication that helps relieve spasms in the gastrointestinal tract and urinary system. While it can provide some relief from the discomfort associated with kidney stones, Tamsulosin is more specifically targeted towards facilitating stone passage. Therefore, while both medications can be helpful, Tamsulosin is more directly related to aiding in the expulsion of the stone.

In terms of your current condition, since you are experiencing only mild swelling without significant pain or hematuria (blood in urine), it is advisable to follow your physician's recommendations. If the swelling persists or worsens, or if you begin to experience pain, you should seek medical attention promptly.
Additionally, it's important to stay well-hydrated, as increased fluid intake can help dilute the urine and may assist in the passage of stones. Aim for a daily urine output of about 2 to 2.5 liters, which can help prevent the formation of new stones and assist in flushing out any existing ones.

Regarding the use of over-the-counter products like Calcium Oxalate Protector, it is essential to approach such supplements with caution. While they may claim to help with stone prevention, their efficacy and safety are not always well-established. It is best to consult with your healthcare provider before starting any new supplement, especially if you have a history of kidney stones.

In summary, Tamsulosin is likely the more appropriate medication for your current situation, as it is designed to assist in the passage of kidney stones. Ketorolac can be reserved for pain management if needed. Always prioritize communication with your healthcare provider regarding any medications or supplements you consider taking, and maintain adequate hydration to support your urinary health.

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