PET Scans for Dementia Diagnosis: A Patient's Guide - Neurology

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Dementia Self-Paid PET Scan


I have a history of type 2 diabetes for 8 years and have been taking tricyclic antidepressants (TCA) and Lyrica for depression for 15 years, but I still experience insomnia and do not achieve deep sleep.
I have a history of smoking.
My grandmother passed away from dementia.
My symptoms include generalized weakness, weakness in all four limbs, unsteady walking, pain in all four limbs, and overall pain that I cannot distinguish between bone pain and muscle pain.
I also experience hand tremors, palpitations, forgetfulness regarding my good friends' names, dates, and the names of frequently visited chain stores.
I forget the names of the president, public figures, mayors, and common celebrities.
I have mild auditory hallucinations, my voice has become softer and slightly hoarse, and I sometimes miss my stop.
My fingers tremble.
1.
I went to a health check center and asked about the results.
The staff said that although the brain was scanned, it could only detect brain tumors and not dementia.
Is this true? The examination items at the health check center include: PET/CT scan, which involves the injection of a radioactive isotope, with a duration of about 90 minutes and a cost of $36,000 for a full-body tumor screening to check for tumors or inflammation in various parts of the body.
2.
If I go to a neurologist and tell the doctor that I want to pay out of pocket for a PET scan, can the doctor arrange it? Because the doctor would know what type of PET scan is necessary, but I am unsure if I should mention that I want to pay out of pocket.
Will the doctor schedule it for me? Thank you, doctor.

Niming, 30~39 year old female. Ask Date: 2020/09/23

Dr. Hong Weibin reply Neurology


Hello: 1.
There are many types of PET scans, and typically, the PET/CT scans performed at health check-up centers are used to detect suspected tumors throughout the body, not to assess for dementia.
2.
You need to check if the hospital offers PET scans for dementia.
Currently, the PET scan used to detect Alzheimer's disease is called Amyloid-PET (amyloid positron emission tomography).
This examination can be used to check for Alzheimer's disease, but it is not covered by health insurance and must be paid for out-of-pocket.
However, dementia has many causes beyond Alzheimer's disease, and a thorough medical history must be taken by a clinical physician.

Reply Date: 2020/09/23

More Info


Understanding PET scans, particularly in the context of dementia diagnosis, can be quite complex, especially for patients with underlying health conditions such as diabetes and depression. Here’s a comprehensive guide to help you navigate this process.


What is a PET Scan?
A Positron Emission Tomography (PET) scan is a type of imaging test that helps doctors observe metabolic processes in the body. In the context of dementia, PET scans are primarily used to assess brain function and identify abnormalities that may indicate conditions like Alzheimer’s disease or Lewy body dementia. The scan involves injecting a small amount of radioactive material (a tracer) into the bloodstream, which is then taken up by active brain cells. Areas of the brain that are less active will show up differently on the scan compared to healthy areas.


Can PET Scans Diagnose Dementia?
While PET scans can provide valuable insights into brain activity and help differentiate between types of dementia, they are not standalone diagnostic tools. They are most effective when used in conjunction with clinical evaluations, patient history, and other diagnostic tests. For instance, the FDG-PET scan measures glucose metabolism in the brain, which can be altered in dementia. However, it is crucial to note that not all PET scans are designed to detect dementia. The standard PET/CT scans often focus on identifying tumors or other structural abnormalities rather than cognitive disorders.


Your Symptoms and Concerns
Given your symptoms—such as memory loss, confusion, and physical weakness—it is understandable to seek further evaluation through a PET scan. Your family history of dementia also adds to the urgency of understanding your cognitive health. However, it is essential to communicate openly with your healthcare provider about your symptoms and concerns. They can help determine whether a PET scan is appropriate for your situation and which specific type of scan would be most beneficial.


The Role of Your Healthcare Provider
When you visit a neurologist or a specialist in cognitive disorders, they will assess your symptoms and medical history. They can order the appropriate tests, including a PET scan if deemed necessary. If you express a desire for a PET scan, the physician can arrange for it, ensuring it aligns with your clinical needs. It is important to remember that the physician will consider various factors, including your diabetes and current medications, before proceeding with the scan.


Preparing for a PET Scan
If a PET scan is scheduled, you will need to follow specific preparation guidelines. Generally, patients are advised to fast for several hours before the scan to ensure accurate results. Your blood sugar levels may also be monitored, especially since you have diabetes. It is crucial to maintain your blood sugar within a safe range before the procedure, typically below 150 mg/dL, to avoid complications during the scan.


Conclusion
In summary, while PET scans can be a valuable tool in diagnosing dementia, they are not definitive on their own. They should be part of a comprehensive evaluation that includes clinical assessments and possibly other imaging techniques. Given your symptoms and medical history, it is advisable to consult with a neurologist who can guide you through the process, recommend the appropriate tests, and interpret the results in the context of your overall health. Early detection and intervention are key in managing dementia and improving quality of life, so seeking professional guidance is a crucial step.

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