Menstrual Pain: When Pain Relief Medications Fail - Obstetrics and Gynecology

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Menstrual pain


Hello, Doctor.
I would like to inquire about menstrual cramps.
Is there a problem if I take painkillers but still experience pain? I have had issues with menstrual cramps before, but taking painkillers usually resolves the pain, and sometimes I don't even need them.
However, this time the pain is so severe that even after taking two pills (spaced 4 hours apart), it hasn't alleviated much.
My menstrual flow is normal, and the color is bright red, not dark red.
Could you help clarify this?

Jenny, 20~29 year old female. Ask Date: 2020/10/13

Dr. Cai Yonglong reply Obstetrics and Gynecology


It could be endometriosis (or a chocolate cyst), and you should visit a gynecology clinic for an examination.

Reply Date: 2020/10/13

More Info


Menstrual pain, also known as dysmenorrhea, is a common condition that many women experience during their menstrual cycles. It can range from mild discomfort to severe pain that interferes with daily activities. When over-the-counter pain relief medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, fail to alleviate menstrual pain, it can be concerning and may warrant further investigation.

There are several potential reasons why you might be experiencing increased menstrual pain despite taking pain relief medications. Here are some considerations:
1. Hormonal Fluctuations: Hormonal changes during your menstrual cycle can affect the severity of pain. Prostaglandins, which are hormone-like substances involved in pain and inflammation, can be elevated during menstruation. Higher levels of prostaglandins can lead to more intense uterine contractions, resulting in increased pain.

2. Underlying Conditions: Conditions such as endometriosis, fibroids, or pelvic inflammatory disease can cause severe menstrual pain. Endometriosis, in particular, occurs when tissue similar to the lining of the uterus grows outside it, leading to significant pain and discomfort. If your pain has changed in intensity or character, it may be worth discussing with your healthcare provider.

3. Medication Tolerance: Over time, some individuals may develop a tolerance to certain pain medications, meaning that the same dose may become less effective. If you have been using the same medication for a long time, it may be necessary to adjust the dosage or switch to a different medication.

4. Timing of Medication: The timing of when you take pain relief medications can also impact their effectiveness. It is often recommended to take NSAIDs at the onset of menstrual pain rather than waiting until the pain becomes severe. If you are waiting until the pain is intense, the medication may not work as effectively.

5. Lifestyle Factors: Stress, lack of sleep, and poor diet can exacerbate menstrual pain. Engaging in regular physical activity, practicing relaxation techniques, and maintaining a balanced diet can help manage pain levels.

6. Consultation with a Healthcare Provider: If your menstrual pain persists despite taking pain relief medications, it is essential to consult with a healthcare provider. They can perform a thorough evaluation, which may include a physical examination, imaging studies, or laboratory tests to rule out any underlying conditions.

7. Alternative Treatments: In addition to traditional pain relief medications, there are alternative treatments that may help alleviate menstrual pain. These can include hormonal contraceptives, which can help regulate menstrual cycles and reduce pain, as well as non-pharmacological approaches such as acupuncture, yoga, or dietary supplements like omega-3 fatty acids.

In summary, while it is common to experience menstrual pain, the fact that your usual pain relief methods are not working as effectively this time could indicate a need for further evaluation. It is essential to monitor your symptoms and discuss any changes with your healthcare provider to ensure appropriate management and treatment. They can help determine the best course of action based on your individual situation and medical history.

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