Pleural Thickening: Next Steps for Lung Health - Pulmonology

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Chest issues


Hello, I had a chest X-ray on October 7, 2020, followed by a CT scan on October 14, 2020.
The radiologist's report noted defined pleural thickening at the left apical lung, with the nature to be determined.
Tumor growth cannot be completely ruled out.
Comparing with the chest X-ray from February 5, 2020, there are indeed differences observed.
Between February 5 and October 7, I experienced no discomfort or any medical diagnoses.
The doctor who reviewed the CT scan mentioned an irregular size of 3 to 4 cm.
I have consulted two doctors, and both have referred the issue back to me.
What should I do regarding biopsy, follow-up, or surgery? Thank you.

Leewei, 40~49 year old female. Ask Date: 2020/10/26

Dr. Jian Shuntian reply Pulmonology


Hello: Without seeing the images, I cannot make a judgment.
You can obtain a copy of all the imaging studies and consult another pulmonologist for a second opinion.
Ultimately, the final decision on the management plan will need to be made by yourself.

Reply Date: 2020/10/26

More Info


Understanding pleural thickening, especially in the context of lung health, is crucial for determining the next steps in management and diagnosis. Based on your CT findings, which indicate defined pleural thickening at the left apical lung, it is essential to approach this situation with a comprehensive understanding of the potential implications.

Pleural thickening can arise from various causes, including inflammatory processes, infections, benign conditions, or malignancies. The fact that the radiologist noted that "tumor growth cannot be ruled out" is significant and warrants further investigation. The presence of pleural thickening, especially if it has changed over time, raises concerns about possible underlying pathology, including the potential for malignancy.

Given that you have had a previous chest X-ray and CT scan that showed changes, it is essential to consider the following steps:
1. Consultation with a Specialist: It is advisable to consult a pulmonologist or a thoracic surgeon who specializes in lung diseases. They can provide a more detailed assessment of your condition and recommend appropriate diagnostic procedures.

2. Further Imaging: Depending on the initial evaluation, additional imaging studies may be warranted. A PET scan, for example, can help determine the metabolic activity of the pleural thickening and whether it is likely to be malignant.

3. Biopsy: If there is a suspicion of malignancy, a biopsy may be necessary to obtain a definitive diagnosis. This can be done through various methods, including:
- CT-guided needle biopsy: This is a minimally invasive procedure where a needle is guided by imaging to obtain a tissue sample from the thickened area.

- Thoracentesis: If there is any fluid present in the pleural space, this procedure can be performed to analyze the fluid for cancer cells or other abnormalities.

- Video-assisted thoracoscopic surgery (VATS): In some cases, a more invasive approach may be required to obtain a tissue sample, especially if the thickening is extensive or if there are other concerning features.

4. Monitoring and Follow-Up: If the initial evaluation does not indicate malignancy, close monitoring may be appropriate. This could involve regular imaging studies to assess for any changes in the pleural thickening over time.

5. Consideration of Symptoms: Although you mentioned that you have not experienced any symptoms, it is essential to remain vigilant for any new symptoms such as persistent cough, chest pain, or shortness of breath, which could indicate a progression of the underlying condition.

6. Multidisciplinary Approach: Engaging a team that includes radiologists, pulmonologists, and oncologists can provide a comprehensive approach to your care. They can collaborate to determine the best course of action based on the findings and your overall health status.

In summary, while pleural thickening can be benign, the potential for malignancy necessitates a thorough evaluation. Engaging with healthcare professionals who can guide you through the diagnostic process is essential. It is understandable to feel anxious about these findings, but taking proactive steps to investigate and monitor your lung health will help in making informed decisions about your care.

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