Atrial Premature Contractions: Causes, Treatment, and Concerns - Cardiology

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Atrial premature contraction (APC)


Dear Dr.
Wu,
In July of this year, I occasionally noticed an irregular pulse, often missing a beat.
After undergoing a Holter monitor test at the hospital, it showed 700 instances of atrial premature contractions (APCs) and one ventricular premature contraction (VPC).
Both echocardiogram and exercise electrocardiogram results were normal.
Currently, I am managing this with a low dose of Inderal (1/2 tablet three times a day), but the APCs still intermittently occur.
I am an avid exerciser and consume a small amount of red wine (about 150cc/day), but I have refrained from both activities due to this condition.

I have the following questions:
1.
What are the causes of atrial premature contractions? Do they naturally resolve over time?
2.
Is it possible to use cardiac electrophysiological studies to induce and then ablate the abnormal discharge points with 3D mapping? What are the success and recurrence rates for this procedure?
3.
Is medication necessary for this condition? What is the likelihood of developing atrial fibrillation in the future?
4.
As I engage in meticulous work, the sensation of missed heartbeats significantly impacts my performance, causing me great concern.
The joy of a good night's sleep seems to have vanished.
I found limited information on your website regarding atrial premature contractions, so I apologize for my inquiries.
Thank you for your response!

Ren Ting, 60~69 year old female. Ask Date: 2020/10/27

Dr. Wu Xueming reply Cardiology


1.
Many factors in daily life can contribute to this condition, such as emotions, stress, irregular sleep patterns, or excessive intake of caffeinated beverages.
2.
Simple atrial premature contractions do not require cardiac electrophysiological testing.
3.
If symptoms affect daily life, medication can be taken.
The likelihood of simple atrial premature contractions evolving into atrial fibrillation is very low.

Reply Date: 2020/10/27

More Info


Atrial premature contractions (APCs), also known as atrial premature beats, are a common type of arrhythmia characterized by early heartbeats originating in the atria. They can be benign in many cases, but understanding their causes, treatment options, and potential concerns is crucial for managing your health effectively.


1. Causes of Atrial Premature Contractions
APCs can arise from various factors, including:
- Electrolyte Imbalances: Low levels of potassium, magnesium, or calcium can lead to increased excitability of the heart muscle.

- Stimulants: Caffeine, nicotine, and alcohol can trigger APCs. In your case, the daily consumption of red wine may contribute to the irregularities.

- Stress and Anxiety: Emotional stress can lead to increased sympathetic nervous system activity, which may provoke APCs.

- Underlying Heart Conditions: Although your echocardiogram and exercise stress test were normal, structural heart issues can sometimes lead to arrhythmias.

- Medications: Certain medications, particularly those that affect heart rhythm, can induce APCs.

In many instances, APCs can occur without any identifiable cause and may resolve spontaneously. However, lifestyle modifications, such as reducing alcohol intake and managing stress, can help decrease their frequency.


2. Electrophysiological Studies and Ablation
Electrophysiological studies (EPS) can be performed to assess the electrical activity of the heart and identify the origin of the premature beats. If APCs are frequent and symptomatic, catheter ablation may be considered. This procedure involves:
- Mapping: Identifying the precise location of the abnormal electrical signals.

- Ablation: Using radiofrequency energy to destroy the tissue responsible for the premature beats.

The success rate for ablation of APCs is generally high, with many patients experiencing significant improvement. However, recurrence can occur, particularly if the underlying triggers are not addressed.


3. Medication Management
The use of beta-blockers, such as Inderal (propranolol), is common for managing APCs, especially when they cause symptoms. While you are currently on a low dose, it may be necessary to adjust your medication based on your symptoms and the frequency of the APCs. Regular follow-up with your healthcare provider is essential to monitor your condition and make any necessary adjustments.


4. Risk of Progression to Atrial Fibrillation
While APCs are generally benign, they can sometimes be a precursor to more serious arrhythmias, such as atrial fibrillation (AF). The risk of progression to AF varies among individuals and is influenced by factors such as:
- Frequency of APCs: Frequent APCs may increase the likelihood of developing AF.

- Underlying Heart Conditions: Structural heart disease or other cardiovascular risk factors can elevate the risk.

- Lifestyle Factors: Continued consumption of stimulants and lack of physical activity may also contribute.


Conclusion
Your concerns regarding the impact of APCs on your daily life, especially in relation to your work and sleep, are valid. It is essential to maintain open communication with your healthcare provider about your symptoms and any lifestyle changes you can implement. Reducing alcohol intake, managing stress, and ensuring adequate hydration and electrolyte balance can be beneficial.

If your symptoms persist or worsen, further evaluation, including potential electrophysiological studies, may be warranted. Remember that while APCs can be concerning, many individuals live normal, active lives with appropriate management. Regular follow-ups and a proactive approach to your health will help you navigate this condition effectively.

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