the Link Between HPV, Cervical Dysplasia, and Vaccination - Obstetrics and Gynecology

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Is there a correlation between cauliflower and cervical cancer?


Hello Dr.
Chang, I have a question regarding my girlfriend who is 28 years old.
This year, she was diagnosed with HPV types 6 and 56.
I understand that type 6 is associated with genital warts.
She has been undergoing treatment for nearly six months, but recently, Chen's clinic asked her to undergo HPV screening and a Pap smear.
The results were abnormal, indicating mild cervical dysplasia and other inflammatory conditions in the vagina.
However, they were unwilling to explain further and mentioned the presence of the high-risk type 56, advising her to transfer to a larger hospital for a biopsy for further examination.
I feel that the medical ethics here are somewhat lacking.
She has been returning weekly for treatment of the genital warts, but they rushed her out after prescribing medication, and only now indicated the abnormal results.
I want to know if this is serious and if she can still receive the nine-valent HPV vaccine during the treatment period to prevent other strains.
I know that types 16, 18, 52, and 58 account for about 90% of cervical cancer cases.
I mention this purely to reassure her, as she might be feeling anxious.
Additionally, the doctor asked her on Saturday if she still wants to have children, which makes me wonder if they are implying that her uterus may not be able to support a pregnancy.
Do you have any good suggestions? What should I ask the doctor directly when we go for her biopsy follow-up at Taoyuan Min-Sheng Hospital next week? Thank you.

Joanne, 20~29 year old female. Ask Date: 2020/11/09

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the human papillomavirus (HPV) often presents with multiple strains co-infecting simultaneously.
The reports you mentioned generally do not indicate the need for major surgery at this stage.
Based on your description, it is advisable to wait for the biopsy results and then discuss them with your physician along with your previous test results and treatment records.
This will help determine the appropriate course of treatment moving forward.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2020/11/09

More Info


Understanding the link between HPV (Human Papillomavirus), cervical dysplasia, and vaccination is crucial for managing reproductive health, especially for women in their late twenties like your girlfriend. HPV is a common sexually transmitted infection, and certain strains, particularly HPV 6 and 56, can lead to various health issues, including genital warts and cervical dysplasia.


HPV and Cervical Dysplasia
Cervical dysplasia refers to the abnormal growth of cells on the surface of the cervix, which can be detected through Pap smears. The abnormal results you mentioned indicate mild cervical dysplasia, which is often categorized as CIN (Cervical Intraepithelial Neoplasia) 1. This condition is typically associated with persistent infection from high-risk HPV types, which can progress to more severe dysplasia (CIN 2 or CIN 3) and potentially lead to cervical cancer if left untreated.

Your girlfriend's diagnosis of HPV 6, which is associated with genital warts (also known as condylomata acuminata), and HPV 56, a high-risk type, necessitates careful monitoring and management. The fact that she has been treated for HPV-related issues for six months but is only now being referred for further evaluation suggests a need for more comprehensive care. It’s essential for healthcare providers to communicate effectively about the implications of abnormal test results and the necessary follow-up actions.


Vaccination Considerations
Regarding the HPV vaccination, it is generally recommended that individuals receive the HPV vaccine before becoming sexually active or before they are diagnosed with HPV-related conditions. However, even if someone has been diagnosed with HPV, vaccination can still provide protection against other HPV types not currently infecting them. The nine-valent HPV vaccine (Gardasil 9) protects against nine strains of HPV, including the high-risk types 16, 18, 52, and 58, which are responsible for a significant percentage of cervical cancers.

In your girlfriend's case, it is advisable to discuss the possibility of receiving the vaccine with her healthcare provider. The vaccine can still be beneficial, even if she is currently undergoing treatment for HPV, as it may help prevent future infections from other HPV types.


Emotional and Psychological Support
Your concern about your girlfriend's emotional well-being is valid. The diagnosis of HPV and cervical dysplasia can be distressing, and it’s important to provide her with support. It’s also crucial to address her fears regarding fertility and the implications of her diagnosis. While mild dysplasia often resolves on its own, ongoing monitoring and treatment are essential to ensure that it does not progress.

When you visit the hospital for her follow-up appointment, consider asking the following questions:
1. What are the next steps in managing her cervical dysplasia? Understanding the treatment plan will help alleviate anxiety about her condition.

2. Is it safe for her to receive the HPV vaccine at this stage? This will clarify whether vaccination is a viable option for her.

3. What are the implications of her current diagnosis for her fertility? This is crucial information, especially if she is considering having children in the future.

4. What lifestyle changes or additional screenings should she consider? This can empower her to take an active role in her health.


Conclusion
In summary, HPV is a significant factor in cervical health, and understanding its implications can help in managing conditions like cervical dysplasia. Vaccination remains a key preventive measure, even for those already diagnosed with HPV. Open communication with healthcare providers and emotional support from loved ones are vital in navigating this challenging situation. Encourage your girlfriend to ask questions and express her concerns during her medical appointments to ensure she receives the best possible care and support.

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