Comparing Birth Control Pills: Nina vs. Yejih for Optimal Results

Issues with switching contraceptive pills?

I previously took oral contraceptives for six months and then stopped for six months.
I am currently resuming the use of oral contraceptives, and the gynecologist prescribed me "Nina" coated tablets.
I mentioned to the doctor that I had previously taken "Yueji" for six months, but the doctor said that Nina would have fewer side effects and would be less likely to cause acne.
The ingredients in Yueji are: each tablet contains 3.000 mg of Drospirenone and 0.030 mg of Ethinylestradiol.
The ingredients in Nina are: each tablet contains 2.0 mg of Cyproterone Acetate and 0.035 mg of Ethinyl Estradiol.
The side effects I experienced with Yueji included reduced menstrual flow and mild depression.
After taking Nina for one month, I have not had any significant emotional issues, but I occasionally experience headaches, stomach pain, and nausea.

Is there a difference in the contraceptive effectiveness of these two options? Are there differences in dosage? If purely considering contraceptive effectiveness, which one would you recommend?
I am nearing the end of my first pack of Nina coated tablets and am unsure whether to continue taking them and observe the effects or switch back to Yueji.
Could you please provide me with some advice?
Additionally, if I decide to switch back, how should I time the transition? If you recommend continuing with Nina, should I start the second pack on the second day of my next menstrual period (since I started the first pack on the second day of my period), or should I adhere to the 21 days on, 7 days off regimen?

Niming, 20~29 year old female. Ask Date: 2020/11/19

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, most contraceptive pills are quite similar; as long as you don't experience any discomfort, you can take them.
Generally, you should start taking the first pill on the fifth day of your menstrual cycle.
Wishing you good health!

Reply Date: 2020/11/19

More Info

When comparing birth control pills like Nina (Nina Membrane Tablets) and Yejih (Yejih Tablets), it’s essential to understand their composition, effectiveness, side effects, and how they fit into your personal health needs. Both of these medications are hormonal contraceptives, but they contain different active ingredients which can lead to varying effects on your body.

Composition and Mechanism:
- Yejih contains Drospirenone (3.000 mg) and Ethinylestradiol (0.030 mg). Drospirenone is a progestin that has anti-androgenic properties, which can help reduce acne and other androgen-related side effects. This formulation is often chosen for women who are concerned about hormonal acne or weight gain.

- Nina, on the other hand, contains Cyproterone Acetate (2.0 mg) and Ethinyl Estradiol (0.035 mg). Cyproterone is also a progestin but is known for its anti-androgen effects, making it beneficial for conditions like polycystic ovary syndrome (PCOS) and severe acne.
Effectiveness:
Both pills are effective for contraception, but the choice between them may depend on individual health profiles and side effects experienced. The effectiveness of both pills in preventing pregnancy is similar when taken correctly, which means taking the pill at the same time every day and following the prescribed regimen.
Side Effects:
You mentioned experiencing some side effects with Yejih, such as reduced menstrual flow and mild depression. With Nina, you have reported occasional headaches, stomach pain, and nausea. It’s important to note that side effects can vary significantly from person to person. Some women may find that one formulation suits them better than another based on their unique hormonal responses.

Recommendations:
1. Continue with Nina: If you have been on Nina for a month and have not experienced significant mood changes or other severe side effects, it may be worth continuing to observe how your body adjusts. It typically takes a few months for your body to adapt to a new hormonal contraceptive.

2. Switching Back to Yejih: If you decide to switch back to Yejih, you should ideally start the new pack after completing the current pack of Nina. This means you would begin taking Yejih on the first day of your next menstrual cycle. If you started Nina on the second day of your period, you would do the same with Yejih.

3. Dosage Schedule: Both pills generally follow a 21 days on, 7 days off regimen. This means you take one pill daily for 21 days, followed by a 7-day break during which you would typically have your period. If you switch to Yejih, maintain this schedule for consistency.

4. Consult Your Doctor: Before making any changes, it’s crucial to consult with your healthcare provider. They can provide personalized advice based on your medical history, current health status, and any side effects you may be experiencing.

In conclusion, both Nina and Yejih are effective contraceptive options, but individual experiences with side effects and health conditions can guide your choice. Monitoring your body's response to Nina and discussing any concerns with your doctor will help you make the best decision for your reproductive health. Always prioritize open communication with your healthcare provider regarding any side effects or concerns you may have while on hormonal contraceptives.

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