Abnormal Health Check Results: Urine Ketones and More - Family Medicine

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Health check-up issues


At the end of September, I underwent a simple health check and found some abnormalities.
I am puzzled by the result of "urine ketones 1+" while other routine urine tests seem to be within normal ranges.
The health check was conducted after 6:30 PM, and I wonder if fasting and hunger could be a factor.
Here are the other test values: pH 6.0, urine protein 10, urine glucose negative, blood urea nitrogen 10, and glomerular filtration rate 97.90.
I would appreciate your clarification on this matter.
Thank you.

Xiao Jia, 30~39 year old female. Ask Date: 2020/11/29

Dr. Wu Zongying reply Family Medicine


Hello: A positive urine ketone test with a result of only 1+ is generally not a cause for concern.
Some individuals may produce ketones in their urine after prolonged fasting or starvation, as the body metabolizes triglycerides into ketones.
If you do not have a history of diabetes, there is typically no need for worry.

Reply Date: 2020/11/29

More Info


When interpreting abnormal health check results, particularly concerning urine ketones, it is essential to understand the context of the findings and the physiological implications behind them. In your case, the presence of "urine ketones 1+" alongside other normal urine parameters raises several points for consideration.

Firstly, ketones in the urine indicate that your body is utilizing fat as a primary energy source instead of carbohydrates. This metabolic state can occur under various circumstances, such as prolonged fasting, low carbohydrate intake, or increased physical activity. Given that your health check was conducted after a period of fasting (after 6:30 PM), this could indeed contribute to the presence of ketones in your urine. When the body is deprived of carbohydrates, it begins to break down fat for energy, resulting in the production of ketones, which are then excreted in the urine.

Your other urine test results appear to be within normal ranges, which is reassuring. The pH of 6.0 is within the typical range (4.5 to 8.0), indicating a normal acid-base balance in your urine. The urine protein level of 10 mg/dL is also considered low and typically does not indicate any significant kidney issues, especially since you have no other abnormal findings. The absence of glucose in your urine is a positive sign, as it suggests that your blood sugar levels are likely well-regulated, reducing the risk of diabetes-related complications.

The blood urea nitrogen (BUN) level of 10 mg/dL is also within normal limits, and a glomerular filtration rate (GFR) of 97.90 mL/min indicates that your kidneys are functioning well. A GFR above 90 is generally considered normal, suggesting that your kidneys are effectively filtering waste from your blood.

Given these results, the presence of ketones may not be alarming, especially if you have not consumed food for an extended period. However, if you experience symptoms such as excessive thirst, frequent urination, fatigue, or nausea, it would be prudent to consult a healthcare professional. These symptoms could indicate a more serious metabolic condition, such as diabetic ketoacidosis, particularly if you have a history of diabetes or other metabolic disorders.

In summary, while the presence of urine ketones can be concerning, in the context of fasting and with normal results in other parameters, it may not indicate a significant health issue. It is always wise to follow up with your healthcare provider for further evaluation if you have ongoing concerns or if your symptoms change. Regular monitoring and understanding of your body’s responses to dietary changes and fasting can help you maintain optimal health.

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