Why Do I Still Have Stomach Pain After H. Pylori Treatment? - Gastroenterology and Hepatology

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Is it still painful after taking medication for Helicobacter pylori?


Hello doctor, I have undergone an upper gastrointestinal endoscopy, and the diagnosis is chronic gastritis and gastroesophageal reflux disease (GERD), caused by Helicobacter pylori.
I am currently on a 14-day course of self-paid medication, but I still experience persistent stomach pain, even waking up at night in pain and unable to sleep.
Is this normal?

Ms. Chen, 20~29 year old female. Ask Date: 2020/12/04

Dr. Yang Zhichao reply Gastroenterology and Hepatology


Hello Ms.
Chen, you have already been seen by a physician.
You can discuss your current issues further with your doctor.

Reply Date: 2020/12/04

More Info


Experiencing persistent stomach pain after treatment for Helicobacter pylori (H. pylori) infection can be concerning and frustrating. It is essential to understand that while H. pylori eradication therapy is effective for many patients, some individuals may continue to experience gastrointestinal symptoms even after the bacteria have been successfully eliminated.
Firstly, it is important to recognize that H. pylori is often associated with conditions like chronic gastritis and peptic ulcers. Even after successful treatment, the stomach lining may still be inflamed or irritated, leading to ongoing discomfort. Chronic gastritis can result in symptoms such as abdominal pain, bloating, and nausea, which may persist for some time after the infection has been treated.
In your case, you mentioned that you have been diagnosed with chronic gastritis and gastroesophageal reflux disease (GERD). Both of these conditions can contribute to ongoing stomach pain and discomfort. GERD, in particular, can cause symptoms like heartburn, regurgitation, and chest pain, which may be mistaken for stomach pain. The inflammation in the stomach lining can also lead to increased sensitivity, making it more likely for you to experience pain after eating or when your stomach is empty.

Another factor to consider is the possibility of functional dyspepsia, a condition characterized by chronic or recurrent pain in the upper abdomen without any identifiable organic cause. This condition can occur even after successful treatment of H. pylori and may require different management strategies.

If you are experiencing severe pain that disrupts your sleep or daily activities, it is advisable to follow up with your healthcare provider sooner rather than later. They may recommend additional diagnostic tests, such as an upper endoscopy or imaging studies, to rule out other potential causes of your symptoms, including ulcers, strictures, or other gastrointestinal disorders.
Moreover, it is crucial to evaluate your current treatment regimen. If you are still experiencing significant symptoms, your doctor may consider adjusting your medications or adding additional therapies. For instance, proton pump inhibitors (PPIs) are commonly prescribed to reduce stomach acid and promote healing of the stomach lining. If you are not already on a PPI, this could be a beneficial addition to your treatment plan.
Lifestyle modifications can also play a significant role in managing your symptoms. Eating smaller, more frequent meals, avoiding trigger foods (such as spicy or fatty foods), and not lying down immediately after eating can help alleviate discomfort. Additionally, managing stress through relaxation techniques or counseling may also be beneficial, as stress can exacerbate gastrointestinal symptoms.

In summary, while it is not uncommon to experience ongoing stomach pain after H. pylori treatment, it is essential to communicate these symptoms with your healthcare provider. They can help determine the underlying cause of your discomfort and develop an appropriate management plan tailored to your needs. Remember, your health and well-being are paramount, and seeking further evaluation and treatment is a proactive step towards finding relief.

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