Myocardial Ischemia: Treatment Options and Next Steps - Cardiology

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Degree of myocardial hypoxia


Hello, doctor! I underwent an exercise electrocardiogram, and my attending physician mentioned myocardial ischemia, recommending either a cardiac catheterization or a CT scan.
However, another doctor suggested that it is mild and that medication would suffice, but then referred me back to my attending physician to prescribe medication.
I would like to know if my report indicates that the condition is mild.
Can I start medication and assess my condition before deciding on the next steps? Here are the report details: Bruce: IIMax.
Workload: 7.00 METs Total exercise time: 5:39 minutes Baseline BP: 144/93 mmHg Baseline HR: 85 bpm Estimated MHR/Age-predicted MHR: 91% Maximal BP: 178/88 mmHg Maximum HR: 141 bpm Result: Positive further horizontal ST depression >=1.0 over V5-V6 at stage III of exercise with total recovery after 5 minutes of rest.

Ms. Zhao, 60~69 year old female. Ask Date: 2020/12/04

Dr. He Dongjin reply Cardiology


Hello, based on a Duke Treadmill Score of -3, you are classified as moderate risk.
The next steps should depend on your symptoms and any changes in your electrocardiogram (ECG), which I have not seen.
Based solely on the report, it indicates moderate risk.
If you are asymptomatic and not concerned, you can choose to observe.
However, if you have any symptoms such as chest tightness or shortness of breath during activity, consider undergoing a CT scan.
We will pray for your safety and well-being at Changhua Hospital.

Reply Date: 2020/12/04

More Info


Understanding myocardial ischemia is crucial for determining the appropriate treatment options and next steps in managing your heart health. Based on the information provided, it appears that you have undergone a series of cardiac evaluations, including a stress test and myocardial perfusion imaging, which have indicated some degree of myocardial ischemia.


Interpretation of Your Results
Your exercise stress test results show that you achieved a maximum workload of 7.00 METs, which is a reasonable level of exertion. However, the presence of horizontal ST depression of 1.0 mm or more in leads V5-V6 during stage III of the exercise indicates that there is a significant concern for ischemia. This ST segment depression is a classic sign of myocardial ischemia, suggesting that your heart muscle is not receiving enough blood flow during exertion.

The recovery of the ST segment after five minutes of rest is a positive sign, indicating that the ischemic response is likely reversible. However, the fact that you experienced this change during exercise suggests that your heart is under stress and may not be functioning optimally under increased demands.


Risk Assessment
The assessment of your myocardial ischemia as "mild" or "moderate" can depend on various factors, including the extent of the ST segment changes, your symptoms, and the presence of other risk factors such as hypertension, diabetes, and family history of heart disease. Given that your baseline blood pressure was elevated (144/93 mmHg), and you have a history of chest pain, it is essential to take these factors into account.


Treatment Options
1. Medication Management: Your doctor has suggested medication as a first-line treatment. This is a common approach for managing mild to moderate ischemia, especially if you are asymptomatic or have manageable symptoms. Medications such as beta-blockers, ACE inhibitors, or statins may be prescribed to help control blood pressure, reduce heart workload, and manage cholesterol levels.

2. Lifestyle Modifications: Alongside medication, lifestyle changes are crucial. This includes adopting a heart-healthy diet, engaging in regular physical activity (as tolerated), quitting smoking if applicable, and managing stress. These changes can significantly impact your overall cardiovascular health.

3. Further Testing: If your symptoms persist or worsen, or if your doctor believes that the ischemia is more significant than initially assessed, further testing such as coronary angiography (heart catheterization) or advanced imaging techniques like a CT coronary angiogram may be warranted. These tests can provide a clearer picture of the coronary arteries and help determine if there are significant blockages that require intervention.


Next Steps
Given the conflicting opinions from different healthcare providers, it is essential to have a thorough discussion with your primary cardiologist. You should express your concerns about the ischemia and the recommendations for further testing versus medication management. It may be beneficial to:
- Request Clarification: Ask your cardiologist to explain the rationale behind the recommendation for either medication or further testing. Understanding the reasoning can help you make an informed decision.

- Monitor Symptoms: Keep a close eye on any symptoms you experience, such as chest pain, shortness of breath, or fatigue. Documenting these can provide valuable information for your healthcare team.

- Follow-Up Appointments: Schedule regular follow-ups to monitor your condition and adjust treatment as necessary. This is crucial for managing your heart health effectively.

In conclusion, while your current assessment may suggest mild ischemia, the presence of ST segment changes during exercise is significant. Medication may be appropriate as an initial step, but ongoing evaluation and possibly further testing should be considered based on your symptoms and overall risk profile. Always prioritize open communication with your healthcare providers to ensure that you receive the best possible care tailored to your needs.

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