Vascular Permeability Issues in Varicose Veins - Cardiology

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Vascular wall permeability issues?


Hello, doctor.
I was previously diagnosed with varicose veins at approximately stages II to III, with pigmentation present.
However, I am uncertain whether the following situation is related to vascular permeability issues.
Whenever I walk for a while, I experience symptoms resembling vascular leakage in my calves, accompanied by a sensation of swelling.
There are large red patches on the skin surface over the areas of varicosity, which disappear after a short rest.
I am wondering if I should undergo additional tests regarding vascular permeability to facilitate treatment.
Thank you!

Xiao Li, 60~69 year old female. Ask Date: 2020/12/07

Dr. Wu Xueming reply Cardiology


For the treatment of varicose veins, please visit the cardiovascular surgery outpatient clinic.

Reply Date: 2020/12/07

More Info


Understanding vascular permeability issues in the context of varicose veins is crucial for managing symptoms and preventing complications. Varicose veins, which are swollen, twisted veins that often appear blue or dark purple, occur when the valves in the veins fail to function properly. This condition can lead to increased venous pressure, resulting in a variety of symptoms, including swelling, pain, and skin changes.

The symptoms you describe—such as the appearance of red patches on the skin, swelling in the lower legs after prolonged walking, and the sensation of heaviness—are indeed consistent with issues related to vascular permeability. When the venous pressure increases, it can cause fluid to leak from the blood vessels into the surrounding tissues, leading to edema (swelling) and skin changes. This phenomenon is often referred to as "venous stasis," where blood flow is impaired, and the pressure in the veins increases, causing fluid to seep out.

The presence of pigment changes in the skin, such as hyperpigmentation, is also a common sign of chronic venous insufficiency, which often accompanies varicose veins. This occurs due to the breakdown of red blood cells that leak into the surrounding tissues, leading to a brownish discoloration of the skin.

Regarding your question about whether further testing for vascular permeability is necessary, it may be beneficial to discuss this with your healthcare provider. While the symptoms you are experiencing are indicative of venous insufficiency, additional tests such as a Doppler ultrasound can provide more information about blood flow in your veins and help assess the severity of the condition. This imaging technique can help visualize the structure of the veins and identify any abnormalities in blood flow, including reflux (backward flow of blood) that may be contributing to your symptoms.

In terms of treatment, managing varicose veins often involves a combination of lifestyle modifications and medical interventions. Here are some strategies that may help alleviate your symptoms:
1. Compression Therapy: Wearing compression stockings can help improve venous return and reduce swelling. These stockings apply pressure to the legs, helping to prevent blood from pooling in the veins.

2. Elevation: Elevating your legs when resting can help reduce swelling and improve circulation. Aim to elevate your legs above the level of your heart for optimal results.

3. Exercise: Regular physical activity, particularly exercises that engage the calf muscles (such as walking or cycling), can help promote venous return and reduce symptoms.

4. Weight Management: Maintaining a healthy weight can reduce the pressure on your veins and improve overall vascular health.

5. Medical Interventions: If conservative measures are insufficient, medical treatments such as sclerotherapy, endovenous laser treatment (EVLT), or surgical options may be considered to address the underlying venous insufficiency.

6. Monitoring Skin Changes: Keep an eye on any changes in your skin, such as new redness, swelling, or ulceration, and report these to your healthcare provider promptly.

In conclusion, your symptoms are likely related to vascular permeability issues associated with varicose veins. While further testing may provide additional insights, implementing lifestyle changes and considering medical treatments can significantly improve your quality of life. Always consult with your healthcare provider to tailor a treatment plan that best suits your individual needs and circumstances.

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