Combining Medications: Can I Take Qianyoujie with Antacids? - Pharmacology

Share to:

Combination of Qianyou medication?


Recently, due to a relapse of depression, my doctor prescribed me with Cymbalta, one capsule in the morning and one in the evening.
I would like to ask if I can take it with a gastric mucosal protectant since it has strong side effects and makes me feel nauseous.
Also, I usually take birth control pills and B vitamins; how long should I wait before taking them? Thank you.

Xiao Xiao, 20~29 year old female. Ask Date: 2020/12/08

Dr. Hou Fangmin reply Pharmacology


Hello, regarding Cymbalta® (duloxetine) side effects: nausea, dry mouth, drowsiness, constipation, and decreased appetite can be quite challenging, but not everyone experiences them.
It's advisable to discuss with your physician how to manage these side effects if you encounter them.
Cymbalta® can interact with alcohol, potentially leading to liver failure or worsening liver disease; therefore, it is not recommended for patients with a history of alcohol abuse or chronic liver disease.
There are no interactions between Cymbalta® and antacids, contraceptives, or B vitamins, so it is safe to take them together.
Wishing you strength and blessings for your health and happiness.

Reply Date: 2020/12/08

More Info


When considering the combination of medications, particularly with a focus on Qianyoujie (also known as "Citalopram" or "Escitalopram"), it is essential to understand both the pharmacological properties of the drugs involved and the potential interactions that may arise.
Qianyoujie is an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class, primarily used to treat depression and anxiety disorders. One of the common side effects of SSRIs, including Qianyoujie, is gastrointestinal discomfort, which can manifest as nausea or vomiting. This is where the question of combining it with antacids arises.

Antacids, such as magnesium hydroxide or aluminum hydroxide, are commonly used to relieve symptoms of heartburn, indigestion, and upset stomach. They work by neutralizing stomach acid, which can provide quick relief from discomfort. However, when taking Qianyoujie, it is crucial to consider the timing of antacid administration.
The general recommendation is to space the administration of Qianyoujie and antacids by at least two hours. This is because antacids can alter the absorption of certain medications, potentially reducing their effectiveness. While there is no direct contraindication for taking Qianyoujie with antacids, maintaining this time gap helps ensure that the antidepressant is absorbed properly and can exert its therapeutic effects without interference.

Regarding your other medications, such as birth control pills and B vitamins, it is also advisable to maintain a similar spacing. Birth control pills typically do not have significant interactions with SSRIs, but taking them at different times can help you remember to take each medication consistently. For B vitamins, there is generally no need for a specific time gap, but taking them with food can enhance absorption and minimize gastrointestinal side effects.

In summary, you can take Qianyoujie with antacids, but ensure to space them out by at least two hours to avoid any potential absorption issues. Additionally, it is important to maintain a consistent schedule for your birth control and B vitamins, which can help manage your overall health and well-being. If you continue to experience significant side effects from Qianyoujie, such as persistent nausea, it is advisable to consult your healthcare provider. They may consider adjusting your dosage or exploring alternative treatments that may be better tolerated.
Always remember that managing medication regimens, especially when dealing with mental health conditions, requires careful attention and communication with your healthcare team. They can provide personalized advice based on your specific health needs and medication history.

Similar Q&A

Understanding Drug Interactions: Can You Safely Combine These Medications?

Hello Doctor, I would like to inquire about potential drug interactions. I have been taking Wankesh for a long time, and recently I developed iritis. My doctor prescribed Pred Forte (prednisolone acetate) eye drops and Salazopyrin enteric-coated tablets. I have had sleep issues, ...


Dr. Hong Yuanbin reply Internal Medicine
Hello, there are no significant interactions between enteric-coated Salazopyrin tablets and neurological medications. However, it is generally recommended to space the administration of different types of medications by 30 to 60 minutes. Thank you for your inquiry.

[Read More] Understanding Drug Interactions: Can You Safely Combine These Medications?


Can You Take Nexium and Strocain Together? Drug Interaction Explained

Could you please clarify if the physician has prescribed two medications? I'm unsure if they can be taken together and whether it will affect their efficacy.


Dr. Cai Anshun reply Gastroenterology and Hepatology
Hello: It is possible to use them simultaneously, but do not take the following medications at the same time: tetracyclines, iron salts, chlorpromazine, levodopa, isoniazid, digoxin, H2-antagonists, indomethacin, nitrofurantoin, and dicumarol. Changhua Hospital cares about your h...

[Read More] Can You Take Nexium and Strocain Together? Drug Interaction Explained


Can I Mix These Medications? Safe Usage Tips for Cold and Joint Drugs

Hello, I have the following two medications. Can I take them together? If not, how should I take them? (1) Cold medication: 1. Acetaminophen 500 mg 2. Oxacain 10 mg 3. Bensau 100 mg 4. Serrapeptase 5 mg 5. Piprinhydrinate 3 mg 6. Iodinated glycerol 60 mg 7. Licorice coug...


Dr. Hou Fangmin reply Pharmacology
Hello; you are taking cold medication which includes Acetaminophen, antacids, antihistamines for runny nose, decongestants, cough suppressants, and anti-inflammatory medications. For your joint pain, you are using muscle relaxants and analgesics. In total, you have 10 different m...

[Read More] Can I Mix These Medications? Safe Usage Tips for Cold and Joint Drugs


Can Traditional Chinese Medicine and Western Drugs Be Taken Together?

Hello, Doctor Gao. Recently, I consulted both Traditional Chinese Medicine and Western Medicine for my tinnitus issue. I would like to ask if the following Chinese and Western medications can be taken simultaneously or if they should not be taken together: Chinese herbal formul...


Dr. Gao Peiyi reply Traditional Chinese Medicine
Currently, there are no cases of interaction effects.

[Read More] Can Traditional Chinese Medicine and Western Drugs Be Taken Together?


Related FAQ

Drug Interactions

(Traditional Chinese Medicine)

Drug Interactions

(Family Medicine)

Drug Interactions

(Gastroenterology and Hepatology)

Drug Interactions

(Cardiology)

Drug Interactions

(Neurology)

Medication Consultation

(Traditional Chinese Medicine)

Drug Interactions

(Psychiatry)

Drug Interactions

(Obstetrics and Gynecology)

Acid Reflux

(Traditional Chinese Medicine)

Medication Consultation

(Pharmacology)