Impact of Chronic Dryness Medication on Pregnancy and Fetal Health - Obstetrics and Gynecology

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I have been taking chronic medication for over two years for Sjögren's syndrome under the care of a rheumatologist. Will this have any impact on the fetus if I become pregnant?


I am in my forties and my menstrual cycle has been delayed for a week and a half.
I experienced lower abdominal pain and visited a doctor, who prescribed me medication to induce menstruation for a week.
The doctor advised me to return for a pregnancy test after a week.
I have been taking medication for dry syndrome for three years.
If I am pregnant, will it affect the fetus? Why can't I take a pregnancy test before taking the medication to induce menstruation? (I am concerned that taking the medication while pregnant could have consequences for the fetus.) Thank you for your response; it would greatly relieve my anxiety.

Nǚshì, 40~49 year old female. Ask Date: 2020/12/10

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, menstrual induction medications generally do not have an impact, and the chances of pregnancy are relatively low at this age.
Wishing you good health.

Reply Date: 2020/12/10

More Info


When it comes to the use of medications during pregnancy, particularly those taken for chronic conditions such as dryness, it is essential to consider both the potential effects on fetal health and the timing of medication use. In your case, you have been taking medication for chronic dryness for three years, and you are concerned about the implications of taking a menstrual induction medication while potentially pregnant.

Firstly, it is important to understand that many medications can have different classifications regarding their safety during pregnancy. The FDA categorizes drugs into categories A, B, C, D, and X, with Category A being the safest and Category X being contraindicated in pregnancy. Medications for chronic dryness may fall into various categories, and their effects can vary significantly.

For instance, if the medication you have been taking for dryness is classified as Category C, it means that risk cannot be ruled out. This classification indicates that animal reproduction studies have shown an adverse effect on the fetus, but there are no adequate and well-controlled studies in humans. Therefore, the use of such medications during pregnancy should be approached with caution and under the guidance of a healthcare provider.

Regarding the menstrual induction medication prescribed to you, it is crucial to know its classification as well. If it is a Category D or X medication, it could pose risks to a developing fetus, including potential birth defects or miscarriage. This is why it is generally advised to confirm pregnancy before starting any new medication, especially those that can induce menstruation.

The reason your doctor may have prescribed the induction medication without confirming pregnancy first could be due to the urgency of your symptoms or the belief that the likelihood of pregnancy was low based on your medical history. However, this approach can indeed be concerning, as taking such medications during early pregnancy can lead to complications.

If you suspect you might be pregnant, it is advisable to take a home pregnancy test before starting any new medication. If the test is positive, you should contact your healthcare provider immediately to discuss your options and the safety of any medications you are currently taking. They may recommend alternative treatments for your chronic dryness that are safer during pregnancy or suggest monitoring your condition without medication until after the pregnancy is confirmed.

In summary, the impact of chronic dryness medication on pregnancy and fetal health can vary widely depending on the specific medication and its classification. It is crucial to communicate openly with your healthcare provider about your concerns and to confirm pregnancy before starting any new medications. If you are pregnant, your healthcare provider can help you navigate the safest options for managing your chronic condition while ensuring the health of your developing fetus. Always prioritize safety and seek professional medical advice tailored to your specific situation.

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