Bilateral Basal Ganglia Echogenicity in Newborn Ultrasound - Neurology

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Cranial ultrasound


Hello, the ultrasound of the newborn's brain shows bilateral basal ganglia echogenicity.
What does this mean? What are the potential impacts? Will it affect intelligence? What abnormalities should we be particularly vigilant about in the baby? Thank you.

Mr. Wang, 50~59 year old female. Ask Date: 2020/12/14

Dr. Jiang Junyi reply Neurology


Hello: You mentioned the presence of echogenic foci on ultrasound, which indicates an area of increased ultrasound echo.
This is typically due to calcification.
There are many causes for basal ganglia calcification in children, including endocrine disorders, hypoxia or anoxia, infections, vascular diseases, or other metabolic factors.
Clinically, symptoms can range from asymptomatic to movement disorders or cognitive dysfunction, as there are numerous potential causes.
When this occurs in infants and young children, it is important to rule out genetic disorders.
I recommend consulting a pediatric neurologist or a genetic disease specialist to discuss further evaluation and treatment.
Wishing you good health and peace.
Dr.
Jiang Junyi, Taoyuan Hospital, cares about you.

Reply Date: 2020/12/14

More Info


Bilateral basal ganglia echogenicity in a newborn ultrasound typically indicates an area of increased echogenicity in the basal ganglia, which can be due to various factors. This finding is not uncommon in neonatal ultrasounds and can often be benign. The basal ganglia are a group of nuclei in the brain involved in motor control, cognition, and emotions. When these areas appear echogenic (brighter on the ultrasound), it may suggest the presence of calcifications, which can occur for several reasons, including hypoxia (lack of oxygen), infections, metabolic disorders, or even normal variations.


Potential Impacts and Symptoms
The presence of bilateral basal ganglia echogenicity can lead to a range of outcomes, depending on the underlying cause. In many cases, especially if the infant is otherwise healthy and developing normally, this finding may not have any significant impact on the child's development or cognitive abilities. However, in some instances, it could be associated with neurological issues, including:
1. Motor Dysfunction: Some infants may experience delays in motor skills or coordination issues.

2. Cognitive Impairment: There is a potential risk for cognitive delays, but this is not guaranteed and varies widely among individuals.

3. Seizures: In some cases, structural brain abnormalities can lead to seizure activity.


Monitoring and Prognosis
The prognosis for infants with bilateral basal ganglia echogenicity largely depends on the underlying cause and the presence of any associated symptoms. If the infant is developing normally at two years of age, as you mentioned, this is a positive sign. Regular follow-up with a pediatric neurologist is advisable to monitor development and to ensure that any potential issues are addressed early. Typically, follow-up ultrasounds or developmental assessments may be recommended until the child reaches a certain age, often around 2-3 years, when more definitive assessments can be made.


Relation to Fontanel Closure
Regarding the anterior fontanel (the soft spot on a baby's head), its closure is a normal part of development and can vary significantly from child to child. The anterior fontanel typically closes between 9 to 18 months of age, and some children may take longer. The presence of an open fontanel does not necessarily correlate with the echogenicity findings in the basal ganglia. If the head circumference is following a normal growth curve and there are no signs of increased intracranial pressure or developmental delays, it is likely just a normal variation.


Reasons for Delayed Closure of the Fontanel
Several factors can contribute to a delayed closure of the anterior fontanel, including:
1. Genetic Factors: Some children may simply have a genetic predisposition for delayed closure.

2. Nutritional Factors: Conditions such as rickets, which is caused by vitamin D deficiency, can affect bone development and fontanel closure.

3. Hydrocephalus: An abnormal accumulation of cerebrospinal fluid can lead to an enlarged head and delayed fontanel closure, but this is typically accompanied by other symptoms.


When to Seek Medical Advice
If your child is currently at the 85-95th percentile for head circumference and has not yet closed the anterior fontanel, it may be wise to consult a pediatric neurologist or a specialist in pediatric development. They can perform a thorough evaluation, including a possible follow-up ultrasound, to ensure that there are no underlying issues that need to be addressed.

In summary, while bilateral basal ganglia echogenicity can be concerning, many infants with this finding go on to develop normally. Continuous monitoring and open communication with healthcare providers are essential to ensure the best outcomes for your child.

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