Antibiotic Use for Epididymitis: Key Questions Answered - Urology

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Recently, after a visit to the urology department, I found out that I have inflammation in the epididymis.
The doctor prescribed antibiotics (Baktar, a combination antibiotic) to be taken twice a day for 7 days, stating that I should complete the course.
However, I accidentally lost one pill.
I've heard from many people that antibiotics should be taken completely, so will missing one pill cause any issues? Do I need to see the doctor again? Additionally, I forgot to take the antibiotic once during breakfast and took it in the evening instead.
Will this have serious consequences? I found that most online resources refer to a three times a day regimen.

simon, 20~29 year old female. Ask Date: 2020/12/18

Dr. Jian Weihong reply Urology


If a dose is missed, it should be skipped and not made up, as taking an excessive dose can be more dangerous.
The most important aspect of completing an antibiotic course is to ensure that the bacteria are completely eradicated to prevent relapse and the development of antibiotic resistance.
However, for most patients, even if a dose is missed or if the treatment is shortened by 1-2 days, the remaining few surviving bacteria typically do not pose a significant problem.

Reply Date: 2020/12/18

More Info


When it comes to the treatment of epididymitis, antibiotics play a crucial role in addressing the underlying bacterial infection. In your case, you were prescribed Baktar (a combination of sulfamethoxazole and trimethoprim) to be taken twice a day for seven days. This medication is effective against a variety of bacterial infections, including those that can cause epididymitis.

Regarding your concerns about missing a dose, it's important to understand how antibiotics work and the significance of completing the prescribed course. Antibiotics are designed to eliminate bacteria, and taking them as directed helps ensure that the infection is fully treated. If you miss a dose, the effectiveness of the treatment can be compromised, as the bacteria may not be completely eradicated, potentially leading to a resurgence of the infection or the development of antibiotic resistance.

1. What happens if you miss a dose?
If you accidentally miss a dose of your antibiotic, the general recommendation is to take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses to make up for the missed one. Missing one dose may not significantly impact your treatment, but it is crucial to maintain a consistent level of the medication in your system.

2. What if you lose a pill?
Losing a single pill from your prescribed course may not drastically affect your treatment, especially if you are otherwise compliant with the regimen. However, if you are concerned about the effectiveness of your treatment due to this loss, it may be wise to consult your healthcare provider. They can assess your situation and determine if you need a refill or an adjustment to your treatment plan.

3. What if you take a dose late?
If you forget to take your antibiotic in the morning and remember to take it in the evening, it is generally acceptable to take it at that time, provided it is not too close to your next scheduled dose. The key is to maintain as regular a schedule as possible. Taking your medication late occasionally should not have a severe impact on your treatment, but consistency is crucial for optimal results.

4. Why is it important to complete the course?
Completing the full course of antibiotics is essential to ensure that all the bacteria are eliminated. Stopping the medication early, even if you feel better, can lead to the survival of some bacteria, which may then become resistant to the antibiotic. This resistance can make future infections harder to treat and can contribute to the broader public health issue of antibiotic resistance.

5. When to seek medical advice?
If you experience any worsening of symptoms, such as increased pain, swelling, or fever, or if you have concerns about your treatment regimen, it is advisable to contact your healthcare provider. They can provide guidance tailored to your specific situation and may recommend further evaluation or a different treatment approach if necessary.

In summary, while missing a single dose or losing a pill may not drastically alter your treatment outcome, it is essential to communicate with your healthcare provider about any concerns. Adhering to your prescribed antibiotic regimen is vital for effectively treating epididymitis and preventing complications. Always prioritize open communication with your healthcare team to ensure the best possible care.

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