Exploring SLOG Therapy for Pancreatic Cancer Treatment in Taiwan

Q: Exploring SLOG Therapy for Pancreatic Cancer Treatment in Taiwan

Hello： There is no standard answer to this treatment question. <br>When it comes to medication options for advanced pancreatic cancer, which is better? Which has fewer side effects? What kind of treatment can the body still tolerate? It all depends on the current situation. <br>I

The effectiveness of SLOG therapy for pancreatic cancer?

Hello, doctor.
My mother is 76 years old.
In July of this year, she experienced abdominal pain and was examined at Cathay General Hospital in Taipei, where she was diagnosed with pancreatic cancer with liver metastasis.
My sisters and I are very anxious, and we transferred her to National Taiwan University Hospital for treatment because they offer multi-CIK immunotherapy.
We spent over a million NT dollars, but it seems to be ineffective as my mother is still experiencing abdominal pain.
Later, I came across information online about a doctor at National Cheng Kung University proposing SLOG therapy, which is said to be suitable for Taiwanese patients.
I am unsure if my mother would be a candidate for this treatment.
She has received gemcitabine, taken TS-1, and undergone immunotherapy, but she is experiencing full-body itching and is at her wit's end.
I am wondering what other treatment options are available for her.
Are there any targeted therapies? We are willing to pay for any treatment that could help my mother!

Pu Pu, 40~49 year old female. Ask Date: 2020/12/23

Dr. Chen Yunfang reply Oncology

Hello: There is no standard answer to this treatment question.
When it comes to medication options for advanced pancreatic cancer, which is better? Which has fewer side effects? What kind of treatment can the body still tolerate? It all depends on the current situation.
I cannot answer this question for you; you need to discuss treatment options and the pros and cons with your attending physician.
Thank you.

Reply Date: 2020/12/23

More Info

SLOG therapy, or "Surgical Laparoscopic Oncological Guidance," is a relatively new approach in the treatment of various cancers, including pancreatic cancer. It is designed to enhance the precision of surgical interventions and improve the overall outcomes for patients. However, the application of SLOG therapy specifically for pancreatic cancer with liver metastasis is still under investigation, and its effectiveness can vary significantly from patient to patient.

In your mother's case, she has been diagnosed with pancreatic cancer that has metastasized to the liver, which is a challenging situation. The standard treatment options for advanced pancreatic cancer typically include chemotherapy, targeted therapy, and immunotherapy. You mentioned that your mother has undergone multiple treatments, including TS-1 (a chemotherapy drug) and immunotherapy, but has not experienced significant relief from her symptoms. This is not uncommon, as pancreatic cancer is known for its aggressive nature and resistance to many treatment modalities.

The fact that your mother is experiencing persistent abdominal pain and has developed skin reactions (itchiness) could indicate that her current treatment regimen is not effectively managing her cancer or its symptoms. It is crucial to communicate these side effects and concerns with her oncologist, as they can provide insights into whether a change in treatment is necessary.

Regarding SLOG therapy, while it may offer some benefits, it is essential to consult with her healthcare team to determine if she is a suitable candidate. Factors such as her overall health, the extent of her disease, and previous treatment responses will play a significant role in this decision. Additionally, SLOG therapy may not be widely available or recognized as a standard treatment for pancreatic cancer in all medical facilities, so it is vital to verify its availability and the expertise of the medical team in administering this therapy.

In terms of alternative treatments, you might want to explore the possibility of clinical trials. Clinical trials often provide access to cutting-edge therapies that are not yet widely available. These trials can include new chemotherapy agents, targeted therapies, or immunotherapies that may be more effective for her specific cancer profile.

Targeted therapies, such as PARP inhibitors or other novel agents, may also be options worth discussing with her oncologist. These therapies are designed to target specific genetic mutations or pathways involved in cancer growth and may offer a more personalized approach to treatment.

It is understandable that you and your family are eager to find effective treatment options for your mother. However, it is crucial to approach this situation with a comprehensive understanding of her medical condition and the potential benefits and risks of any new treatment. Engaging in open discussions with her healthcare team, exploring all available options, and considering second opinions from other oncologists can help you make informed decisions about her care.

In summary, while SLOG therapy may be a potential avenue for treatment, it is essential to evaluate its appropriateness for your mother's specific situation with her healthcare providers. Additionally, exploring clinical trials and discussing alternative therapies may provide further options in her treatment journey. Your mother's comfort and quality of life should remain a priority as you navigate these challenging decisions.

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