Is Kinetin the Secret to Wrinkle-Free Skin? Benefits and Where to Buy

Wrinkle reduction and anti-aging?

I came across Kinetin online.
It is said that Kinetin has the advantage of being non-irritating compared to other anti-wrinkle ingredients, while still achieving anti-aging effects and enhancing the skin's own moisturizing ability.
This means that the skin becomes smoother, finer, and appears younger and healthier.
Is this true? Can it be purchased at hospitals? If not, where can it be bought? I am 33 years old; is it too early for me to use it?

WING, 30~39 year old female. Ask Date: 2000/12/14

Dr. Zheng Lizhen reply Dermatology

Kinetin (N(6)-furfuryladenine) is a plant growth hormone that can delay the aging of plant cells.
In "in vitro" experiments, it has been found that furfuryladenine can delay the aging of human fibroblasts, leading to its use as an anti-aging and wrinkle-reducing skincare ingredient.
Because it does not produce the peeling, redness, and burning sensations commonly associated with retinoid products, and it is not photosensitive, it is generally better tolerated.
However, whether furfuryladenine truly has the claimed effects remains to be seen, as we are only observing the results from "in vitro" studies.
The American company ICN has a product containing Kinetin called "KINERASE." According to a study conducted by the University of California, this product has been found to reduce transepidermal water loss and significantly improve fine lines, spots, and skin roughness (Note: this product also contains vitamin C and other moisturizing ingredients).
This product is not yet widely available in Taiwan, and its effectiveness is still under observation.
If you are eager to try it, you can contact the consumer consultation hotline at 080-095533.

Reply Date: 2000/12/14

More Info

Kinetin, also known as N(6)-furfuryladenine, is a plant-derived cytokinin that has garnered attention for its potential anti-aging properties. It is believed to delay cellular aging, and some studies suggest that it may improve skin texture, reduce the appearance of fine lines, and enhance hydration. The appeal of Kinetin lies in its reported lack of irritation compared to other common anti-aging ingredients, such as retinoids, which can cause redness, peeling, and sensitivity, particularly in individuals with sensitive skin.

Research has shown that Kinetin can help improve skin hydration and elasticity, which are crucial factors in maintaining a youthful appearance. In vitro studies have indicated that Kinetin can promote the proliferation of fibroblasts, the cells responsible for producing collagen and elastin in the skin. This could potentially lead to firmer and more resilient skin. Additionally, Kinetin is thought to have antioxidant properties, which can help protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution.

However, it is essential to note that while the initial findings are promising, most of the research on Kinetin has been conducted in vitro or in animal models. There is still a need for more extensive clinical trials to confirm its efficacy and safety in humans. The product Kinerase, which contains Kinetin, has been studied and shown to reduce transepidermal water loss, improve skin roughness, and diminish the appearance of fine lines. However, it is often combined with other active ingredients, such as Vitamin C, making it difficult to attribute the results solely to Kinetin.

As for availability, Kinetin products like Kinerase may not be widely available in hospitals or clinics, as they are typically sold through dermatology offices, specialty skincare retailers, or online platforms. If you are interested in trying Kinetin, you may want to look for reputable online retailers or consult with a dermatologist who can provide guidance on the best products for your skin type and concerns.

Regarding your age, starting a skincare regimen that includes Kinetin at 33 is not too early. In fact, many dermatologists recommend beginning anti-aging treatments in your early 30s to help prevent the signs of aging before they become more pronounced. Incorporating Kinetin into your skincare routine can be a proactive step towards maintaining youthful skin. However, it's always wise to consult with a dermatologist before introducing new products, especially if you have sensitive skin or specific skin concerns.

In summary, Kinetin shows promise as an anti-aging ingredient with minimal irritation, but more research is needed to fully understand its benefits. It can be found in products like Kinerase, which may be available through dermatologists or online. Starting to use Kinetin at 33 is reasonable, and it may help you achieve smoother, more hydrated skin over time. Always consider professional advice to tailor your skincare routine to your individual needs.

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