Do Stomach Medications Affect the Efficacy of Birth Control Pills? - Obstetrics and Gynecology

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Do stomach medications affect the efficacy of antidepressants?


I took Vomiting Relief Tablets 10mg and Gascon Tablets 40mg tonight when I was feeling unwell.
Will this affect the efficacy of my medication, Yejie? (I have been taking Yejie for a month, and I took the stomach medication on the fourth day of my second month of Yejie.) Thank you.

Ms. Lee, 20~29 year old female. Ask Date: 2021/01/08

Dr. Chen Zhiyu reply Obstetrics and Gynecology


In response to your concerns, the pharmacological effects of routine gastric medications differ from those of hormonal preparations and should not interfere with each other.
Thank you for your inquiry, and I wish you health and happiness.

Reply Date: 2021/01/08

More Info


When it comes to the interaction between stomach medications and birth control pills, it's important to understand how these medications work and their potential effects on each other. In your case, you mentioned taking medications like "吐寧錠" (which is likely an anti-nausea medication) and "加斯克兒錠" (which is a proton pump inhibitor or similar type of medication) while also using a birth control pill.

Generally, most stomach medications, particularly those that reduce stomach acid like proton pump inhibitors (PPIs) or H2 blockers, do not significantly affect the efficacy of hormonal contraceptives. The primary concern with birth control pills is their absorption in the gastrointestinal tract. Some medications can alter the absorption of the hormones in birth control pills, but this is usually not the case with standard stomach medications.

For example, medications like Nexium (esomeprazole) and other PPIs are designed to reduce stomach acid and are not known to interfere with the hormonal components of birth control pills. The same applies to many anti-nausea medications, which primarily work by blocking certain receptors in the brain and do not typically affect the absorption of oral contraceptives.

However, there are some exceptions. Certain antibiotics, for example, can affect the gut flora and potentially alter the metabolism of hormones, leading to reduced effectiveness of birth control pills. Additionally, medications that induce liver enzymes can also decrease the effectiveness of hormonal contraceptives.
In your specific case, since you are taking the birth control pill "悅己" (which is likely a combination of estrogen and progestin), and you have taken the stomach medications on the fourth day of your second month of use, it is unlikely that these medications will have any significant impact on the effectiveness of your birth control.
It's also worth noting that if you experience gastrointestinal issues such as vomiting or severe diarrhea, this could potentially affect the absorption of the birth control pill. If you vomit within two hours of taking the pill, it may not be fully absorbed, and you might need to take another pill.
In conclusion, based on current medical knowledge, the stomach medications you mentioned should not affect the efficacy of your birth control pills. However, if you have ongoing concerns or experience any unusual symptoms, it is always best to consult with your healthcare provider for personalized advice. They can provide guidance based on your specific health situation and any other medications you may be taking.
Maintaining open communication with your healthcare provider is crucial, especially when managing multiple medications. They can help ensure that your treatment plan is safe and effective, addressing both your gastrointestinal issues and your contraceptive needs.

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