Do Antibiotics Like AZTRIN and Tarvid Affect Birth Control Effectiveness? - Obstetrics and Gynecology

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Medications for urinary tract infections and contraceptive pills?


I would like to ask if the medications AZTRIN 250mg and Tarvid 100mg will affect the efficacy of birth control pills?

Kris, 20~29 year old female. Ask Date: 2021/01/14

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello,
Medications that may interact with oral contraceptives include:
1.
Antibiotics (Penicillin, Cephalosporins, Erythromycin, Sulfonamides, Bactrim, Chloramphenicol) - These may reduce the gut flora that aids in absorption, thereby decreasing the effectiveness of contraceptives.

2.
Sedatives (Barbiturates) - These can increase the metabolism of contraceptives, reducing their effectiveness.

3.
Antiepileptic drugs (Primidone, Phenytoin, Carbamazepine) - These also increase the metabolism of contraceptives, leading to decreased effectiveness.

4.
Tuberculosis medications (Rifampicin, Isoniazid)
5.
Antidiabetic medications (Rosiglitazone)
6.
Acetaminophen and Ascorbic acid (Vitamin C) - These may inhibit the metabolism of estrogen, potentially increasing its concentration and the occurrence of side effects.

7.
Oral contraceptives can affect the action of anticoagulants.

8.
Smoking - This can increase the metabolism of contraceptives, reducing their effectiveness.

The antibiotics you mentioned may indeed have an impact, so it is recommended to use additional contraceptive measures during this cycle.
Thank you! Wishing you safety and health.

Dr.
Zhang

Reply Date: 2021/01/14

More Info


When considering the interaction between antibiotics such as AZTRIN (Azithromycin) and Tarvid (Trovafloxacin) with birth control pills, it is essential to understand how these medications can potentially affect the effectiveness of hormonal contraceptives.

Antibiotics can interact with birth control pills in various ways. Historically, certain antibiotics, particularly those that significantly alter gut flora or liver enzyme activity, have been known to reduce the effectiveness of oral contraceptives. For instance, antibiotics like Rifampicin and some anti-seizure medications can increase the metabolism of contraceptive hormones, leading to decreased effectiveness and a higher risk of unintended pregnancy.

However, the specific antibiotics you mentioned, AZTRIN and Tarvid, have different profiles. AZTRIN, which is a macrolide antibiotic, has not been shown to significantly affect the efficacy of hormonal contraceptives. Studies indicate that Azithromycin does not interfere with the metabolism of estrogen or progestin, the active components in most birth control pills. Therefore, if you are taking AZTRIN, it is generally considered safe concerning the effectiveness of your birth control.

On the other hand, Tarvid, which is a fluoroquinolone antibiotic, also does not have a well-documented interaction with hormonal contraceptives. While fluoroquinolones can have various side effects, they do not typically affect the metabolism of contraceptive hormones in the same way that some other antibiotics do.

That said, it is crucial to consider that while these antibiotics may not directly reduce the effectiveness of birth control pills, any condition that leads to vomiting or severe diarrhea can potentially affect the absorption of the contraceptive. If you experience gastrointestinal issues that prevent the proper absorption of your birth control pill, this could inadvertently lead to reduced effectiveness.

In summary, both AZTRIN and Tarvid are not known to significantly impact the effectiveness of birth control pills. However, it is always prudent to consult with your healthcare provider regarding any medications you are taking, especially if you have concerns about potential interactions. They can provide personalized advice based on your health history and current medications.

Additionally, if you are ever in doubt about the effectiveness of your birth control while taking any new medication, consider using a backup contraceptive method, such as condoms, until you can confirm with your healthcare provider that your birth control remains effective. This precaution can help ensure that you maintain effective contraception during your treatment.

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