Concerns About Moles on the Penis: Risks of Melanoma and Treatment Options - Dermatology

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Penile melanocytic nevus


Hello doctor, I have had two moles near the base of my penis since childhood, and I am concerned about the possibility of them becoming melanoma.
I would like to know if removing them with laser treatment would eliminate the risk of melanoma.
If the moles are removed, does that mean that area will no longer be at risk for melanoma? Additionally, if surgery is required, will it involve circumcision?

Mr. Huang, 20~29 year old female. Ask Date: 2021/01/17

Dr. Wu Yuxin reply Dermatology


Complete excision is necessary to minimize the risk of recurrence.

Reply Date: 2021/01/17

More Info


When it comes to concerns about moles on the penis, particularly regarding the risk of melanoma, it is essential to approach the situation with caution and informed understanding. Moles, or nevi, can vary in appearance and characteristics, and while many are benign, changes in their appearance can sometimes indicate a risk for melanoma, a serious form of skin cancer.

Firstly, it is crucial to understand the characteristics of moles that may warrant further investigation. The ABCDE rule is a helpful guideline for assessing moles:
- Asymmetry: One half of the mole does not match the other.

- Border: The edges are irregular, ragged, or blurred.

- Color: The color is not uniform and may include shades of brown, black, or even red, white, or blue.

- Diameter: The mole is larger than 6mm (about the size of a pencil eraser).

- Evolving: The mole is changing in size, shape, or color.

If your moles do not exhibit these characteristics, they are likely benign. However, if you have concerns about their appearance or if they have changed over time, it is advisable to consult a dermatologist or a healthcare provider specializing in skin conditions. They can perform a thorough examination and may recommend a biopsy if there is any suspicion of melanoma.

Regarding the treatment options, laser removal of moles is one method, but it is essential to note that laser treatment may not always be suitable for all types of moles, especially if there is a concern about melanoma. In cases where melanoma is suspected, surgical excision is typically the preferred method. This involves removing the mole along with a margin of surrounding skin to ensure that any potentially cancerous cells are also removed.
As for your question about whether removing the mole eliminates the risk of melanoma in that area, the answer is somewhat nuanced. If a mole is determined to be benign and is completely excised, the risk of melanoma in that specific mole is eliminated. However, it is important to remember that new moles can develop over time, and other factors such as sun exposure and genetic predisposition can influence the risk of developing melanoma in the future.

Regarding the surgical procedure, whether or not the foreskin (prepuce) needs to be removed depends on the location and size of the mole. If the mole is located at the base of the penis and is large or requires significant excision, the surgeon may recommend circumcision or partial circumcision to ensure complete removal and to facilitate healing. This decision should be made in consultation with your healthcare provider, who can assess your specific situation and provide personalized recommendations.

In summary, if you have concerns about moles on your penis, it is crucial to seek professional medical advice. A dermatologist can evaluate the moles, determine if they pose any risk, and discuss the most appropriate treatment options. Regular skin checks and monitoring for changes in moles are essential for early detection of any potential issues, including melanoma. Always prioritize your health and well-being by consulting with qualified healthcare professionals.

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