Menstrual Irregularities and Medication Side Effects: A Gynecological Concern - Obstetrics and Gynecology

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Menstrual issues, medication side effects?


Hello, doctor.
I started treatment for elbow tendinitis in September of last year, and after completing the treatment at the end of October, I stopped since there was no pain.
However, I experienced a recurrence about a week after my menstrual period ended, but the flow was lighter, brownish, and lasted only a few days.
In January of this year, the tendinitis recurred, and I began treatment again.
This situation happened again after two weeks of continuous treatment, and I am wondering if the medications could be affecting this, or if I need to see a gynecologist for an examination? (My menstrual cycle has always been very regular.) During this period, I have used/injected the following medications: Celebrex (celecoxib) 200 mg, Sandoz suspension for injection, Shou Ru Jin tablets, Esomeprazole 60 mg (Asemeprazole), Famatidine enteric-coated tablets 20 mg, and Meloxicam 7.5 mg.

FF, 20~29 year old female. Ask Date: 2021/01/25

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if there is still abnormal bleeding, it is recommended to see a gynecologist.
Wishing you good health.

Reply Date: 2021/01/25

More Info


Menstrual irregularities can be concerning, especially when they deviate from your usual cycle. In your case, you have experienced unusual bleeding patterns after starting treatment for elbow tendonitis, which raises the question of whether the medications you have taken could be influencing your menstrual cycle.

Firstly, it is important to recognize that various medications can indeed affect menstrual cycles. Non-steroidal anti-inflammatory drugs (NSAIDs), such as the ones you mentioned (like Meloxicam), can sometimes lead to changes in menstrual flow or timing. Additionally, corticosteroids, which may be included in your treatment for tendonitis, can also have effects on the menstrual cycle, potentially leading to irregularities.
The medications you listed, including "Celebrex" (Celecoxib), "Sandoz" (likely a reference to a brand of medication), and "Esomeprazole," are primarily used for pain management and inflammation. While they are not typically associated with significant menstrual irregularities, individual responses to medications can vary widely. The occurrence of brown discharge shortly after your period could indicate old blood being expelled from the uterus, which can happen for various reasons, including hormonal fluctuations or changes in the uterine lining.

Given that you have a history of stable menstrual cycles, the recent changes you are experiencing could be attributed to the medications you have taken. However, it is also essential to consider other factors that could contribute to menstrual irregularities, such as stress, changes in weight, or underlying health conditions.
If the irregularities persist or worsen, it would be prudent to consult with a gynecologist. They can perform a thorough evaluation, which may include a physical examination, blood tests to check hormone levels, and possibly imaging studies to assess the reproductive organs. This will help rule out any underlying conditions such as polyps, fibroids, or hormonal imbalances that could be contributing to your symptoms.

In summary, while the medications you have taken for tendonitis could potentially influence your menstrual cycle, it is essential to consider a comprehensive approach to your health. Monitoring your symptoms and seeking medical advice if they persist will ensure that any underlying issues are addressed appropriately. Your gynecologist can provide tailored advice and treatment options based on your specific situation, helping you to regain your menstrual regularity and overall well-being.

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