Interactions Between Emergency Contraceptives, Menstrual Induction Drugs, and Weight Loss Supplements - Obstetrics and Gynecology

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Interactions between emergency contraceptive pills, menstrual induction medications, and weight loss supplements?


Hello, doctor.
I am seeking medication to induce my menstrual cycle from the obstetrics and gynecology department this week, and I will be taking the contraceptive pill "Yueji" afterward.
I would like to ask if it is safe to continue taking my usual dietary supplements for weight loss and breast enhancement, which include:
1.
Ingredients: Bitter melon extract, konjac extract, okra, agar powder, turmeric, magnesium glycinate, inulin, gelatin (gelatin, titanium dioxide, glycerin, food coloring #6, food coloring #7, food coloring #1, purified water, sodium lauryl sulfate).
Dosage: 1-2 capsules on an empty stomach upon waking.
2.
Ingredients: Chili pepper (capsaicin, beta-carotene, niacin, amino acids), chitosan, guarana extract, garcinia cambogia extract, citrus polyphenols (blood orange, grapefruit, orange), fennel, fenugreek seeds, cassia seeds, alginic acid, vitamin B, capsules (gelatin, titanium dioxide, glycerin, food coloring red #6, purified water, sodium lauryl sulfate).
Dosage: 1 capsule before breakfast, with a maximum of 2 capsules per day.
3.
Breast enhancement product ingredients: Japanese patented royal jelly, Japanese patented glutathione, US patented pomegranate extract, Italian collagen peptides, Australian sheep placenta, German non-GMO soybean lecithin, Thai pueraria mirifica extract, evening primrose oil, deglycosylated soybean isoflavones, yam extract, green papaya powder extract, angelica extract, and ligusticum wallichii extract.
Can I continue taking these dietary supplements after taking the menstrual induction medication or the contraceptive pill, or should I space them out? Thank you for your patience in reading and responding.

Yun-Jie, 20~29 year old female. Ask Date: 2021/01/29

Dr. Chen Zhiyu reply Obstetrics and Gynecology


In response to your concerns, many female friends often find themselves troubled by the dilemma of whether to space out or avoid taking health supplements and medications.
In fact, these products that claim to be health-promoting or beneficial are categorized under food regulations.
As they are classified as food, the only issue is whether the additives are appropriate, unlike medications which have concerns regarding dosage.
However, the most worrying aspect is whether the ingredients contained in these foods are honestly and accurately represented on the packaging.
In other words, even if health issues arise, it is difficult to fully attribute them to a specific drink or supplement.
Given this, health supplement manufacturers are not obligated to provide specific experimental data and reports regarding interactions with conventional medications, such as enhancing or diminishing pharmacological effects.
Ultimately, it relies on individual reactions after consumption to make judgments, akin to conducting a living human trial between health supplements and medications.
With this explanation, I believe you may have new insights.
Thank you for your question, and I wish you health and happiness.

Reply Date: 2021/01/29

More Info


When considering the interactions between emergency contraceptives, menstrual induction drugs, and weight loss supplements, it is essential to understand how these substances can affect each other and your overall health.
Firstly, emergency contraceptives, such as levonorgestrel or ulipristal acetate, are designed to prevent pregnancy after unprotected intercourse. They work primarily by delaying ovulation. Menstrual induction drugs, often prescribed to regulate or induce menstruation, can have various active ingredients that may influence hormonal levels in the body.
In your case, you mentioned taking menstrual induction medication and subsequently using a contraceptive pill. Generally, hormonal contraceptives can interact with other medications, particularly those that affect liver enzymes responsible for drug metabolism. However, most menstrual induction drugs do not significantly impact the efficacy of emergency contraceptives or regular contraceptive pills.
Regarding the weight loss supplements you listed, they contain various natural ingredients, such as bitter melon extract, konjac extract, and turmeric. While these ingredients are generally considered safe, their effects on hormonal balance and metabolism can vary. For instance, some ingredients may have mild diuretic effects or influence blood sugar levels, which could indirectly affect hormonal medications.
Here are some key points to consider:
1. Timing and Separation: It is advisable to space out the intake of different medications and supplements. For example, if you take your menstrual induction medication, wait a few hours before taking your contraceptive pill or weight loss supplements. This separation can help minimize any potential interactions.

2. Consultation with Healthcare Providers: Always inform your healthcare provider about all the medications and supplements you are taking. This includes over-the-counter products and herbal supplements. They can provide personalized advice based on your health history and current medications.

3. Monitoring for Side Effects: When combining different medications and supplements, be vigilant for any unusual side effects. If you experience any adverse reactions, such as changes in your menstrual cycle, unexpected bleeding, or gastrointestinal issues, consult your healthcare provider immediately.

4. Natural Supplements and Hormonal Medications: While many natural supplements are safe, some can have hormonal effects. For instance, phytoestrogens found in soy and other plants can mimic estrogen in the body. If your weight loss supplements contain such ingredients, they may interact with hormonal medications, potentially altering their effectiveness.

5. Dietary Considerations: Certain foods and beverages can also affect the metabolism of medications. For example, grapefruit juice is known to interact with various drugs by inhibiting liver enzymes. While your listed supplements do not specifically mention grapefruit, it is wise to be cautious about dietary choices when on hormonal medications.

In conclusion, while there are generally no significant interactions between emergency contraceptives, menstrual induction drugs, and the weight loss supplements you mentioned, it is crucial to approach this combination with caution. Always consult with your healthcare provider for tailored advice, and ensure you monitor your body's response to any new combination of medications and supplements. This proactive approach will help maintain your health and ensure the effectiveness of your contraceptive methods.

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