Can I Resume My Accutane Treatment After a Six-Month Break?

After discontinuing oral isotretinoin?

Hello Doctor, I started taking isotretinoin in January of the year before last as part of a treatment regimen.
However, my skin became excessively dry, so my doctor advised me to take 10 mg every other day instead.
Last August, I went to Green Island for a month and often forgot to take my medication.
Since then, I haven't taken it at all, and I have about 40 capsules left, which means I'm nearing the end of my treatment.
Given that it has been almost six months, can I continue taking it from where I left off, or should I start the treatment over again? Thank you, Doctor.

Zhuang, 20~29 year old female. Ask Date: 2021/02/06

Dr. Wu Yuxin reply Dermatology

I am not clear about the severity of your acne before and after; this is a question you should ask your attending physician, as they are most familiar with your condition.

Reply Date: 2021/02/06

More Info

When considering the resumption of Accutane (isotretinoin) treatment after a six-month break, it is essential to approach the situation with caution and under the guidance of a healthcare professional. Accutane is a powerful medication primarily used to treat severe acne, and it comes with a range of potential side effects and risks, particularly concerning pregnancy and liver function.

First, it is crucial to understand that isotretinoin has a cumulative effect on the body. If you have been off the medication for six months, your body may have changed in response to the absence of the drug. This includes potential changes in your skin condition, hormonal levels, and overall health. Therefore, before resuming treatment, it is advisable to consult with your dermatologist or healthcare provider. They can assess your current skin condition, review your medical history, and determine whether it is safe and appropriate for you to continue with the remaining doses of Accutane.

In many cases, if a significant amount of time has passed since the last dose, your doctor may recommend starting a new course of treatment rather than simply picking up where you left off. This is because the effectiveness of the medication can vary based on how long you have been off it, and your doctor may want to ensure that you are receiving the optimal dosage for your current condition.

Additionally, it is essential to monitor for any side effects that may arise upon resuming treatment. Common side effects of Accutane include dry skin, chapped lips, and increased sensitivity to sunlight. More severe side effects can include liver function abnormalities and changes in mood or mental health. Regular follow-up appointments and blood tests may be necessary to monitor your liver function and lipid levels while on isotretinoin.

If you decide to resume treatment, it is also vital to adhere to the guidelines provided by your healthcare provider regarding dosage and frequency. Accutane is typically prescribed in a specific regimen, and deviating from this can affect its efficacy and safety.

In summary, while it may be possible to resume your Accutane treatment after a six-month break, it is crucial to consult with your healthcare provider first. They will help you determine the best course of action based on your current health status and skin condition. Always prioritize safety and follow medical advice when dealing with potent medications like isotretinoin.

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