Drug interactions and the efficacy of contraceptives?
Hello Doctor, I have two important questions that I'm very concerned about regarding the effectiveness of my birth control pills this month.
1.
My last menstrual period started on January 19.
I have already completed three full packs of the birth control pills (Mestinon) and this month is the fourth pack.
I took the first pill of this pack on January 24.
Last night, on February 6, about 1.5 hours after taking the pill, I experienced severe vomiting, so I took an additional pill.
I had sexual intercourse with my boyfriend on February 4 and 5, and there was one instance of unprotected sex on February 5, but he had already ejaculated very little by then.
I'm worried whether the vomiting and taking an extra pill will affect the effectiveness of the birth control.
2.
Due to inflammation of my wisdom tooth, today (February 8), my doctor prescribed me medication for two days, including antipyretics, anti-inflammatories, and stomach medication, with the most important being Amoxicillin 500mg.
I took the first two medications after meals, but at night, I didn't think much and took the Amoxicillin, stomach medication, and the other two medications together with my birth control pill.
Will this affect the effectiveness of the birth control pill? Also, will these mistakes I made this month significantly decrease the effectiveness of my birth control and increase the chances of pregnancy? Thank you for your response, Doctor.
I'm really worried...
Xiao Tang, 10~19 year old female. Ask Date: 2021/02/08
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it generally does not have an impact, and the chances of pregnancy should be low.
Wishing you good health.
Reply Date: 2021/02/08
More Info
When it comes to the effectiveness of birth control pills, several factors can influence their efficacy, particularly drug interactions and gastrointestinal disturbances. In your case, you have raised two significant concerns regarding potential impacts on your birth control effectiveness due to vomiting and the concurrent use of antibiotics.
1. Vomiting After Taking Birth Control Pills: If you vomited within two hours of taking your birth control pill, it is generally recommended to take another pill as soon as possible. Since you mentioned that you vomited 1.5 hours after taking the pill and subsequently took another one, you have taken the correct steps to mitigate the risk of reduced effectiveness. However, if vomiting occurs more than two hours after taking the pill, the pill is likely to have been absorbed, and no additional action is necessary. Given that you had unprotected intercourse on February 5, it is essential to consider the timing of your pill intake and the vomiting incident. Since you took the pill on February 6 and vomited shortly after, it is possible that the pill was not fully absorbed, which could lead to a decrease in contraceptive effectiveness.
2. Antibiotics and Birth Control Pills: Regarding the use of amoxicillin, it is important to note that most studies indicate that common antibiotics, including amoxicillin, do not significantly affect the effectiveness of hormonal contraceptives. However, there are exceptions, particularly with certain antibiotics that can induce liver enzymes and potentially lower hormone levels. In your case, since you took amoxicillin along with your birth control pill, it is unlikely that this will have a significant impact on the effectiveness of your contraceptive method. Nevertheless, it is always prudent to use additional contraception (like condoms) during the course of antibiotic treatment, especially if you have concerns about interactions.
Key Considerations:
- Timing and Absorption: The timing of your vomiting in relation to when you took your birth control pill is crucial. If the pill was not absorbed due to vomiting, it could lead to a risk of pregnancy if you had unprotected intercourse shortly before or after that incident.
- Antibiotic Interaction: While amoxicillin is not typically associated with reduced effectiveness of birth control pills, it is wise to monitor any unusual symptoms or changes in your menstrual cycle that could indicate a potential issue.
- Additional Precautions: Given the circumstances, it would be advisable to use a backup method of contraception for at least seven days after any incident of vomiting or if you are taking antibiotics, just to be safe.
Conclusion:
In summary, while your vomiting incident could potentially affect the effectiveness of your birth control pill, your prompt action to take another pill is a positive step. The use of amoxicillin is unlikely to significantly impact your birth control effectiveness, but it is always best to err on the side of caution. If you continue to have concerns or experience any unusual symptoms, please consult with your healthcare provider for personalized advice and guidance. Remember, maintaining open communication with your healthcare provider about all medications you are taking is essential for ensuring effective contraceptive use.
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